简介:AbstractObjective:To investigate cumulative live birth rate (cLBR) per oocyte retrieval in infertile patients aged 40 years and over undergoing their first in vitro fertilization/intracytoplasmic sperm injection cycles and to identify the possible predictors.Methods:A total of 1,613 patients at a university hospital in China from January 2013 to May 2017 were enrolled in this retrospective study. All data for fresh and subsequent frozen-thawed cycles were analyzed. Multivariate logistic regression analysis with stepwise selection of possible predictors for cLBR was performed, and Loess curve was constructed to determine the association between cLBR and the number of oocytes retrieved.Results:cLBR significantly increased with the number of oocytes retrieved and reached up to 75% when > 20 oocytes were retrieved (P < 0.001). Variables of antral follicle count (AFC) and the number of oocytes retrieved were selected using multiple logistic regression analysis with stepwise selection to predict the significance of cLBR. cLBR demonstrated an obvious upward trend as the number of oocytes retrieval increased in the Loess curve.Conclusions:For patients aged 40 years and over, AFC and the number of oocytes retrieved were two key predictors for cLBR and maximization of ovarian reserve exploitation was pivotal to increase the chance of live birth.
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简介:AbstractBackground:More and more scholars have called for the cumulative live birth rate (CLBR) of a complete ovarian stimulation cycle as a key indicator for assisted reproductive technology. This research aims to study the CLBR of the first ovarian hyperstimulation cycles and analyze the related prognosis factors that might affect the CLBR.Methods:Our retrospective study included first in vitro fertilization or intracytoplasmic sperm injection (IVF/ICSI) cycles performed between January 2013 to December 2014. A total of 17,978 couples of first ovarian hyperstimulation IVF/ICSI cycles were included. The study was followed up for 4 years to observe the CLBR. The multivariable logistic regression model was used to analyze the prognosis factor, P value of <0.05 was considered statistically significant.Results:The cumulative pregnancy rate was 58.14% (10,452/17,978), and the CLBR was 49.66% (8928/17,978). The female age was younger in the live birth group when compared with the non-live birth group (30.81 ± 4.05 vs. 33.09 ± 5.13, P < 0.001). The average duration of infertility was shorter than the non-live birth cohort (4.22 ± 3.11 vs. 5.06 ± 4.08, P < 0.001). The preliminary gonadotropin used and the total number of gonadotropin used were lower in the live birth group when compared with the non-live birth group (both P < 0.001). Meanwhile, the number of oocytes retrieved and transferrable embryos were both significantly higher in the live birth group (15.35 ± 7.98 vs. 11.35 ± 7.60, P < 0.001; 6.66 ± 5.19 vs. 3.62 ± 3.51, P < 0.001, respectively).Conclusions:The women’s age, body mass index, duration of infertility years, infertility factors, controlled ovarian hyperstimulation protocol, the number of acquired oocytes, and number of transferrable embryos are the prognosis factors that significantly affected the CLBR.
简介:Peer-to-peer(P2P)technologyprovidesacost-effectiveandscalablewaytodistributevideodata.However,highheterogeneityoftheP2Pnetwork,whichrisesnotonlyfromheterogeneouslinkcapacitybetweenpeersbutalsofromdynamicvariationofavailablebandwidth,bringsforwardgreatchallengetovideostreaming.Toattackthisproblem,anadaptiveschemebasedonrate-distortionoptimization(RDO)isproposedinthispaper.WhilelowcomplexityRDObasedframedroppingisexploitedtoshapebitrateintoavailablebandwidthinpeers,thestreamedbitstreamisdynamicallyswitchedamongmultipleavailableversionsinanRDOwaybythestreamingserver.SimulationresultsshowthattheproposedschemebasedonRDOachievesgreatgaininoverallperceivedqualityoversimpleheuristicschemes.
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简介:ASpecializedCommitteeofREInforma-tionundertheChineseRESocietyhasbeenformedwiththepurposeofstreng-theningtheexchangeofREinformationandpromotingthedevelopmentofREsci-enceandtechnologyathomeandabroad.ThefirstmeetingofthecommitteewasheldinBeijingonDecember23-25,1989,andwasattendedbyover100representa-tivesfromuniversitiesandscientificresearchinstitutionsinvariouspartsofChina.Amongthemweresomewell-knownscholarswhohavelongbeenengagedin
简介:In1946,WorldWarⅡhadjustrecentlyended.Moreandmorepeoplewerefloodingtosportingevents,especiallycollegebasketball.MaxKase,asportseditoroftheNewYorktoldtheowneroftheNationalHockeyLeague,WalterBrown,abouthisidea,andBrowntookthei-deatoNedIrish.Nedstatedhewasalreadyworkingonsuchaleague,andKasedideventuallyreceiveseveralthousanddollarsforhisefforts.