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简介：Thisletterstudiesandanalyzestheworkingfeaturesofmaincircuitoftri-levelboostPowerFactorCorrect(PFC)converterandtheadvantagesoftri-levelswitchconverterinaspectsofbearinghigh-voltageofpowercomponents,overallsystemlossandmagneticcomponentselectionbaseduponthesingle-levelboostPFCswitchconverter.Besides,relyingontheapplicationofmi-croprocessorinpowerconvertertechnologyandDSP(DigitalSignalProcessing)chip'sstrongcal-culatingcapacity,theletterpresentstheadoptionofmodifiedschemeoftri-levelboostPFCconverterunderthecontrolofpredictivecontrolalgorithm.Moreover,theoperatingprincipleandcontrolmethodarespecified,theresultsofcircuittestandanalysisareprovidedandtheadvantagesofpre-dictivecontroltechnology-basedmulti-levelboostPFCconverterisverified.

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简介：BACKGROUND:Culturesfrommultipleportionsofumbilicalcordbloodmesenchymalstemcellshavebeenshowntoundergomorerapidproliferationandattachmentthansingleportions.OBJECTIVE:Toobservegrowthofbasicfibroblastgrowthfactor(bFGF)-inducedculturesofhumanamnion-derivedmesenchymalstemcells(AMSCs)anddifferentiationintoneuronal-likecells.DESIGN,TIMEANDSETTING:Comparativeobservation.ThestudywasperformedattheLaboratoryofMicrobiologyandImmunology,BasicMedicalSchoolofZhengzhouUniversityfromJanuarytoMay2008.METHODS:Amniafromfull-term,uterine-incisiondeliveryweredonatedby12healthywomen.AMSCswereobtainedbycellseparationandculturetechniques,andwerepassagedandinducedbybFGF.Fromthethirdpassage,atotalof1mLAMSCs,atadensityof1.0×10~4/mL,wasseparatelyharvestedfromsixsamples,whichservedasgroupA.Atotalof1mLAMSCs,atadensityof1.0×10~4/mL,washarvestedseparatelyfromtheremainingsixsamples,whichservedasgroupB.Atotalof0.5mLfromthesixsamplesofgroupAand0.5mLfromthesixsamplesofgroupBwerecombinedtoformgroupC.MAINOUTCOMEMEASURES:Differencesincellquantityamongthethreegroupswerecomparedbycellquantificationand3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazoliumbromide(MTT)analysis.Expressionofaglialcellmarker,neuron-specificenolase,andnestinwasdetectedinthethreegroupsbyimmunocytochemistry.RESULTS:CellquantificationandMTTanalysisoflivecells,aswellasAMSCabsorbance,weresignificantlygreateringroupCcomparedwithgroupsAandBat18daysofculture(P<0.05),andnosignificantdifferencewasobservedbetweengroupsAandB.Glialfibrillaryacidicprotein,neuron-specificenolase,andnestinwereexpressedinallgroupsfollowingbFGFinduction.CONCLUSION:MixedAMSCculturespromotedproliferation,andbFGF-inducedAMSCsdifferentiatedintoneuronal-likecells.

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简介：文章讨论了Factor定理的一些应用,特别对Auslander转置作了讨论.

简介：1毫无疑问，当2009年的德尔·波特罗在美网连续击败纳达尔和费德勒夺得冠军的时候，他就已经成为了打破巨头垄断的最好人选，可惜右手腕的伤病延缓了他的脚步，虽然在伤病恢复之后他的世界排名短暂来到过史上最高第四的位置，

简介：Asanresearchexampleofthewidelyexistingcooperation-competitionsystems,theauthorspresentanempiricalinvestigationonafruitnutritivefactornetwork.Itisdescribedbyanode-weightedbipartitegraph.Thefruitnutritivefactorsaredefinedasthenodes,andtwonodesareconnectedbyanedgeifatleastonefruitcontainsthesetwonutritivefactors.Thefruitsaredefinedasthecollaborationacts.Thenode-weightW_(nt),whichsignifiesthe'importancedegree'ofeachactornode,isdefinedasthecontentofanutritivefactorinafruit.Theempiricalinvestigationresultsshowsomeuniquefeatures.Thenode-weightdistributionstakeso-called'shiftedpowerlaw'functionforms,buttheact-weightdistributiontakesanormalform.Thedegreeandact-degreedistributionsshowimpulsive-spectrumlikeforms.Theseobservationsmaybehelpfulforthestudyoffruits.Thenetworkdescriptionmethodproposedinthisarticlemaybeuniversalforakindofcooperation-competitionsystems.

简介：Itisstandardpractice,wheneveraresearcherfindsanewgene,tosearchdatabasesforgenesthathaveasimilarsequence.Itisnotstandardpractice,wheneveraresearcherfindsanewgene,tosearchforgenesthathavesimilarexpression(coexpression).Failuretoperformco-expressionsearcheshasleadtoincorrectconclusionsaboutthelikelyfunctionofnewgenes,andhasleadtowastedlaboratoryattemptstoconfirmfunctionsincorrectlypredicted.WepresentheretheexampleofGliaMaturationFactorgamma(GMF-gamma).Despiteitsname,ithasnotbeenshowntoparticipateingliamaturation.ItisageneofunknownfunctionthatissimilarinsequencetoGMF-beta.ThesequencehomologyandchromosomallocationledtoanunsuccessfulsearchforGMF-gammamutationsinglioma.WeexaminedGMF-gammaexpressionin1432humancDNAlibraries.Highestexpressionoccursinphagocytic,antigen-presentingandotherhematopoieticcells.WefoundGMF-gammamRNAinalmosteverytissueexamined,withexpressioninnervoustissuenohigherthaninanyothertissue.OurevidenceindicatesthatGMF-gammaparticipatesinphagocytosisinantigenpresentingcells.Searchesforgeneswithsimilarsequencesshouldbesupplementedwithsearchesforgeneswithsimilarexpressiontoavoidincorrectpredictions.

简介：Asingle-particlemicrobeamfacilityhasbeenconstructedattheLaboratoryofIonBeamBioengineering(LIBB),ChineseAcademyofSciences.Thesystemisdesignedtodeliverthedefinednumberofhydrogenions,coveringarangeofenergyfrom1.0to3.5MeV,intoanareasmallerthanthenucleiofindividuallivingcells.AccuracyoftheparticledetectionsystemandthecelltargetingsysteminthefacilityhasbeenassessedusingCR39(nucleartrackdetector)for2.3MeVprotons.Theresultsdemonstratethattheparticledetectionefficiencyisabove98%,andtheoveralltargetingaccuracyofthemicrobeamislimitedwithin3μmformorethan90%hits.

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简介：AHamiltoniank-factorisak-factorcontainingaHamiltoniancycle.Ann/2-criticalgraphGisasimplegraphofordernwhichsatisfiesδ(G)≥n/2andδ(G-e)

简介：translationitselfisaculture,Thelanguageisacountryculturecarrier,thetranslationofafilmlikefillingaword

简介：Thegrowthofdevelopingcountriesisanimportanteventofhistoricsignificanceinthecurrentworld.Withthechangesoftheconditionsofthetimes,theirpoliticalandeconomicpursuits

简介：ＦｒｅｑｕｅｎｃｙｒｅｓｐｏｎｓｅｏｆｔｉｌｔｍｅｔｅｒｓａｎｄｔｉｄａｌｆａｃｔｏｒＪＵＮＹＡＮＧ（杨军）ＳｅｉｓｍｏｌｏｇｉｃａｌＢｕｒｅａｕｏｆＪｉａｎｇｓｕＰｒｏｖｉｎｃｅ，Ｎａｎｊｉｎｇ２１００１４．ＣｈｉｎａＡｂｓｔｒａｃｔＴｈｅｒｅｌａ...

简介：Objective:Tostudytheexpressionofactivatedepi-dermalgrowthfactorreceptor(EGFR)andtranscrip-tionfactorE2F(E2F)inCondylomaAccuminata(CA)patients.Methods:ImmunofluorescenttechniqueswereusedtoinvestigatetheexpressionofactivatedEGFRandE2FinCApatients.Results:TheexpressionofactivatedEGFRonthemembraneofepithelialcellsinCAlesionswassig-nificantlygreatercomparedtoexpressionleversinthecontrolgroup(P<0.01).Moreover,theco-expres-sionofactivatedEGFRandE2Fwassignificantlyin-creasedcomparedtothecontrolgroup(P<0.01).Conclusion:Ourobservationssuggestthatthein-creaseinactivatedEGFRexpressionmaystimulatehyperplasiainCApatientsthroughtheactivationoftranscriptionfactorE2F.

简介：Objective:Tostudytheexpressionlevelsofplatelet-derivedgrowthfactor(PDGF)andgranulocytecolony-stimulatingfactor(G-CSF)inperipheralbloodandtheirroleinthepathogenesisofCondylomaacuminatum(CA).Methods:Seraweretakenfrom70patientswithCondylomaacuminatumandcomparedwith35healthycontrols.PDGFandG-CSFinserumwerequantitatedusingadualantibodysandwichenzyme-linkedimmunoabsorbentassay(ELISA).Results:SerumconcentrationsofPDGFandG-CSFweresignificantlyincreasedinpatientswithCondylomaacuminatum(CA)comparedtocontrols(P<0.001andP<0.005respectively).SerumlevelsofPDGFandG-CSFcorrelatedwithclinicalseverityofCA,butnosignificantdifferencewasobservedbetweendifferentdurationofdiseasegroups.AsignificantpositivecorrelationwasnoticedbetweenneutrophilcountandG-CSFlevels(γ=0.38,P<0.001),andtheneutrophilcountshowednosignificantcorrelationwithPDGF.Conclusion:TheresultsindicatedthatincreasedexpressionofPDGFandG-CSFinperipheralbloodmightbeinvolvedinpathogenesisofCA.

简介：客观：为了与M-CSFR验证MAF-J6-1受体的抗原协会并且进一步学习M-CSF和它的受体的角色，调停了在支持白血病的房间增长的juxtacrine。方法：MAF-J6-1RRE2的Monoclonal抗体(McAb)和rhM-CSFR的polyclonal抗体(PolyAb)被准备。到M-CSFR的McAbRE2的特性被ELISA被间接ELISA，有J6-1房间殖民地形成的跨neutralizing试金和中立化测试证实。结果：到M-CSFR的净化的RE2的反应活动是超过1：16000。M-CSFR和MAF-J6-1R的禁止的活动能被RE2和anti-M-CSFR抗体堵住。到M-CSFR的RE2的反应能被M-CSFR减少。结论：到M-CSFR的RE2的特性被证实，有M-CSFR的MAF-J6-1R的抗原协会被证明。它建议M-CSF和它的受体调停了auto-juxtacrine刺激能是在白血病或nonhematological恶意的起作用的机制。

简介：Variousworkhardeningmechanisms,onthebasisoftheircharacteris-tics,areclassifiedintotwocategories:thepile-uphardeningandthetanglehardening.Togetherwithadiscussionabouttheexperimentalinvestigationsofworkhardening,thedescriptionsforthosetwobasichardeningmechanismsaresuggested,respectively.Combiningthesedescriptions,anewsinglecrystalhardeninglawisproposed,whichcanbeusedtodescribeworkhardening,particularlythecyclichardeningofacrystalgraininapolycrystallinematerial.Furthermore,somerelevantdiscussiononthenewsinglecrystalhardeninglawisalsomadeinthispaper.