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简介：Asingle-particlemicrobeamfacilityhasbeenconstructedattheLaboratoryofIonBeamBioengineering(LIBB),ChineseAcademyofSciences.Thesystemisdesignedtodeliverthedefinednumberofhydrogenions,coveringarangeofenergyfrom1.0to3.5MeV,intoanareasmallerthanthenucleiofindividuallivingcells.AccuracyoftheparticledetectionsystemandthecelltargetingsysteminthefacilityhasbeenassessedusingCR39(nucleartrackdetector)for2.3MeVprotons.Theresultsdemonstratethattheparticledetectionefficiencyisabove98%,andtheoveralltargetingaccuracyofthemicrobeamislimitedwithin3μmformorethan90%hits.

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简介：Variousworkhardeningmechanisms,onthebasisoftheircharacteris-tics,areclassifiedintotwocategories:thepile-uphardeningandthetanglehardening.Togetherwithadiscussionabouttheexperimentalinvestigationsofworkhardening,thedescriptionsforthosetwobasichardeningmechanismsaresuggested,respectively.Combiningthesedescriptions,anewsinglecrystalhardeninglawisproposed,whichcanbeusedtodescribeworkhardening,particularlythecyclichardeningofacrystalgraininapolycrystallinematerial.Furthermore,somerelevantdiscussiononthenewsinglecrystalhardeninglawisalsomadeinthispaper.

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简介：ABSTRACT:Westudytheevolutionofsingleellipticvortexringforinitialaspectratio(AR)=2,4,6.TheincompressibleNavier-Stokesequationsaresolvedbyadealiasedpseudo-spectralmethodwith64~3gridpointsinaperiodiccube.WefindthattherearethreekindsofvortexmotionasARincreasesandvortexbifurcationoccursatacertainAR.Theprocessesofadvection,interaction,anddecayofvortexringareanalyzed.Numericalresultscoincidewithexperimentsandothernumericalsimulations.

简介：Anewsimilarsingle-differencemathematicalmodel(SS-DM)anditscorrespondingalgorithmareadvancedtosolvethedeformationofmonitoringpointdirectlyinsingleepoch.ThemethodforbuildingtheSSDMisintroducedindetail,andthemainerrorsourcesaffectingtheaccu-racyofdeformationmeasurementareanalyzedbriefly,andthebasicalgo-rithmandstepsofsolvingthedeform-ationarediscussed.Inordertovalidatethecorrectnessandtheaccuracyofthesimilarsingle-differencemodel,thetestwithfivedualfrequencyreceiversiscarriedoutonaslidewaywhichmovedinplaneinFeb.2001.Inthetest,fivesessionsareobserved.Thenumericalresultsoftestdatashowthattheadvancedmod-eliscorrect.

简介：AbstractObjective:Pemphigus is a life threatening autoimmune bullous disease which involves the skin and mucous membranes of the stratified squamous epithelium. The global distribution of Pemphigus varies according to genetic, ethnic, socioeconomic, and cultural backgrounds. The purpose of our study is to evaluate the epidemiological features of pemphigus a single center in Morocco and compare our results with those reported elsewhere.Methods:A retrospective analysis was conducted of 302 pemphigus patients seen between 1990 and 2020 in the Dermatology Department of Ibn Sina Hospital (Rabat, Morocco). We further collected all the Moroccan scientific researches published by now to compare.Results:The average annual incidence was 0.32/100,000 inhabitants. The incidence doubled to 0.72 in 2020. The most common variant was pemphigus vulgaris (125 cases) followed by pemphigus erythematosus (99 cases), pemphigus foliaceous (40 cases), and vegetans (27 cases). The female to male ratio was 0.75, the average age at onset was 53 years old and the mean duration of the disease before diagnosis was 13.36 months.Conclusion:This study joins the main characteristics of pemphigus in the Maghreb and around the world (pemphigus vulgaris most frequent subtype). In 2020, an epidemiological peak occurred during the coronavirus disease 2019 pandemic; probably related to stress and delayed time consultation for fear of contracting the severe acute respiratory syndrome coronavirus 2.

简介：Thispaperdealswithamethodologyforsinglegatelocationoptimizationforplasticinjectionmold.Theobjectiveofthegateoptimizationistominimizethewarpageofinjectionmoldedparts,becausewarpageisacrucialqualityissueformostinjectionmoldedpartswhileitisinfluencedgreatlybythegatelocation.Featurewarpageisdefinedastheratioofmaximumdisplacementonthefeaturesurfacetotheprojectedlengthofthefeaturesurfacetodescribepartwarpage.Theoptimizationiscombinedwiththenumericalsimulationtechnologytofindtheoptimalgatelocation,inwhichthesimulatedannealingalgorithmisusedtosearchfortheoptimum.Finally,anexampleisdiscussedinthepaperanditcanbeconcludedthattheproposedmethodiseffective.

简介：Inthispaper,asingle-columnstructureusedaswell-headplatformisstudied.Theloadsofwaveandcurrentexertedonthesingle-columnwillbegreatlyreduced,thereforethecostofthestructurewillbedecreased.Theadvantagesofthesingle-columnstructurecomparedwithordinaryjacketstructureareexplained.Adynamicanalysisofthistypeofstructureismadeandsomeproblemsrelatedtodynamicanalysisaresolved.Inordertocheckthereliabilityofcomputationtheoryandprogramme,modeltestshavebeencarriedout.However,asspaceislimited,theconclusionoftestswillbeintroducedinanotherpaper.Therefore,thistypeofstructureisapplicableforprocticalengineering.

简介：TheangledependenceofopticalphononmodesofanAlNbulksinglecrystalfromthem-plane（1100）andc-plane（0001）surfaces,respectively,isinvestigatedbypolarizedRamanspectroscopyinabackscatteringconfigurationatroomtemperature.CorrespondingRamanselectionrulesarederivedaccordingtomeasuredscatteringgeometriestoillustratetheangledependence.Theangle-dependentintensitiesofphononmodesarediscussedandcomparedtotheoreticalscatteringintensities,yieldingtheRamantensorelementsofA1（TO）,E22,E1（TO）,andA1（LO）phononmodesandtherelativephasedifferencebetweenthetwocomplexelementsofA1（TO）.Furthermore,theRamantensorofwurtziteAlNiscomparedwiththatofwurtziteZnOreportedinpreviouswork,revealingtheintrinsicdifferencesoflatticevibrationdynamicsbetweenAlNandZnO.

简介：Anovelsingle-polarizationsingle-modephotoniccrystalfiber(SPSM-PCF)withcircularandellipticalair-holesisproposed.ThecharacteristicsoftheproposedSPSM-PCFareinvestigatedbyusingafull-vectorfiniteelementmethod(FEM)withperfectmatchedlayer(PML)boundaryconditions.TheresultsshowthattheSPSMoperationisachievedwithwiderband,andthetotaldispersionprofileoftheSPSM-PCFisdispersion-flattenedfrom1.193μmto1.384μm.ThisdispersionpropertymakestheproposedSPSM-PCFusefulforvariousapplications,suchasopticaltransmissionanddispersioncompensationforconventionalfiberatlongwavelengthbandwith500nmnegativedispersionregion.ItindicatesthatthisisagoodsolutiontorealizebroadbandSPSMoperation.

简介：AbstractBackground:The incidence of uterine cesarean scar defect (niche) is high, and some patients require surgery. Single-port laparoscopy can reduce post-operative pain, and provide better cosmetic effects. This study was performed to evaluate the safety and superiority of single-port laparoscopy-assisted vaginal repair of uterine cesarean scar defect (niche) in women after cesarean section.Methods:This study included 74 patients who were diagnosed with uterine cesarean niche at the Shanghai First Maternity and Infant Hospital from January 2013 to June 2015. Thirty-seven patients underwent single-port laparoscopy-assisted vaginal surgery as the case group, and the remaining patients underwent vaginal repair surgery as the control group. We collected data from the inpatient and follow-up medical records. The clinical characteristics of these two groups were compared. The odds ratios and 95% confidential intervals were calculated for each variable by univariate and multivariate analyses.Results:Patients who underwent single-port laparoscopy-assisted vaginal repair had a significantly longer operation time (2.3 [2.0-2.7] vs. 2.0 [1.6-2.3] h, P = 0.015), shorter gas passage time (1.2 [1.0-1.5] vs. 1.7 [1.0-2.0] days, P = 0.012), shorter hospital stay (3.1 [3.0-4.0] vs. 4.5 [4.0-6.0] days, P = 0.019), and fewer complications (0 vs. 4 cases). Univariate analysis showed that depth of the niche (P = 0.021) the mild adhesiolysis score (P = 0.035) and moderate adhesiolysis score (P = 0.013) were associated with the bladder injury. Multivariate analysis showed that the moderate adhesiolysis score (P = 0.029; 95% confidence interval, 1.318-3.526) was the strongest independent predictor of bladder injury.Conclusion:This study confirmed the safety and superiority of single-port laparoscopy-assisted vaginal repair of uterine cesarean scars.

简介：我们建议被用来在single-j壳的Hamiltonian决定联合参数C的一个修改公式。与以前已知的公式比较，新公式改进在入侵者single-j层次和尼尔逊之间的协议。为在粒子转子模型以内的chiral乐队的研究，新联合参数将更加影响在马甲乐队之间切开的精力。

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简介：-Thispaperpresentsacalculationmethodforthediffractionofbothregularwavesandirregularwavesofthesingledirectionalfrequencyspectrumbehindasinglejettywithatheoreticalanalysis,whichhasbeenconfirmedthroughthemodelexperiments,derivesamethodofcomputingthediffractedirregularwavesbehindthesinglejettywiththetheoreticalanalysisonthebasisofcomputationofthefielddataandgivestheformulasandthefiguresofthecomputationofwavediffractionsbehindtheverticalwallormoundsinglejetties.

简介：Effectsofpressureand/ormagnetismonthecriticalsuperconductingtemperature(Tc)ofδ-MoNsinglecrystalwereinvestigatedusingaMaglabsystem.Theδ-MoNsinglecrystalwassynthesizedatextremeconditionsofhighpressureandhightemperature.Thecarrierdensityofδ-MoNsinglecrystalasafunctionofappliedpressurewasdeterminedusingHallcoefficientmeasurement.

简介：控制并且操作单个fluorophores的荧光具有对为它在改进分子的photonics和分子的电子学的表演的潜在的使用的最近的年的大兴趣，例如在基于单个分子的器官的轻射出的设备，单个光子来源，器官的地效果晶体管，和探针或传感器。这评论显示出单个器官的分子的荧光排放怎么能用金属性的nanostructures和electric-field-induced电子转移的本地电磁的领域被修改。荧光开关的Electric-field-induced荧光调整，磁滞现象，和成就详细被讨论。