简介：Inthispaper,theselectiveadsorptionofLDLonchitosanmodifiedwithPEGandAsp.wasstudied.TheadsorptionrateofLDLandHDLonthedoublemodifiedchitosanwas57%and12%respoectively,TheresultsshownthatthedoublemodifiedchitosancanbeusedaadsorbentforselectivebindingtoLDL,thisworkmayhelptodevelopfunctionalcolumnsforhemoperfusion.

简介：

简介：Modifieddiphenyloxideresinwassynthesizedbyco-polymerizationofunsaturatedacidanddiphenyloxidederivants.Andthenmodifiedbismaleimideresinandexpoxidelinearphenolicresinwereaddedintomodifieddiphenyloxideresintoco-polymerizeandmodifyoncemore.Thesystemwasappliedincomposites.Theirpropertieswereinvestigatedandfoundthattheymettherequirementsasaheat-resistingadhesive.

简介：

简介：Macroporousmethylacrylate-divinylbenzenecopolymersweresynthesizedandmodifiedbypolyethylenepolyamine.TheaminoacylasefromAspergillusoryzaewasadsordedonthesemodifiedcopolymers.Theroleofcertainfactorssuchasdegreeofcross-linking,amountofporegenicsolvent,modifyingagentandporestructures,intheactivityofimmobilizedaminoacylasewasstudied.EffectsofadsorptiontimeandamountofenzymeusedontheactivityofaminocylaseimmobilizedonMMD-12-13werealsoinvestigated.ThecolumnofaminoacylaseimmobilizedonMMD-12-13waspreparedandN-acyl-DL-methioninewasresolvedcontinuouslyforamonth,theremainingactivitywasstillover90%.

简介：

简介：Thesurfaceofpolypropylene(PP)membranewasmodifiedbylowtemperatureplasmawithammonia.Theeffectofexposuretimewasinvestigatedbymeansofcontactanglemeasurement.Theresultsshowthatlowtemperatureammoniaplcsmatreatmentcanenhanceitshydrophilicity.Chinesehamsterovary(CHO)cellsattachmentonthemodifiedmembranewasenhancedandthegrowthrateonthemembranewasfasterthanunmodifiedone.

简介：

简介：

简介：

简介：Polyethylenimine-polyL-lysinePEI-PLL共聚物经由PEI开始的L离氨酸N-carboxyanhydrideLysZ-NCA的戒指洞聚合被综合。有siRNA的PEI-PLL的complexation被粒子尺寸和希腊语的第六个字母潜力大小学习。流动cytometric分析和共焦的成像显示出它的优秀细胞内部的trafficking能力。PEI-PLL在vitro比商业PEI-25k显示了更高的基因silencing效率和更低的cytotoxicity。在antitumor学习，PEI-PLL进一步与siVEGF被相结合并且显然为CT26肿瘤模型的处理显示出肿瘤抑制效果。因此，PEI-PLL是在vivo的进一步的antitumor处理的一个有希望的siRNA搬运人候选人。

简介：Threepolymericadsorbentswithhydrogenbondingacceptors,methylamine,N-methyl-acetamideandaminotri(hydroxymethyl)methanemodifiedresinsaresynthesizedfromchloromethylatedX-5resin.AdsorptionisothermsofphenolandtheophyllineontothethreemodifiedresinsandtheoriginalX-5resinfromaqueoussolutionaremeasured.TheresultsshowthatadsorptionofcompoundswithhydrogenbondingdonorontomethylamineandN-methylacetamidemodifiedresinsisenhancedascomparedwiththatontoX-5resin,andadsorptionmechanismbetweentheadsorbentsandtheadsorbatesismainlybasedonhydrogenbondingandhydrophobicinteraction.Whileadsorptionofcompoundswithhydrogenbondingdonorontoaminotri(hydroxymethyl)methanemodifiedresinisloweredascomparedwiththatontoX-5resin,andadsorptionmechanismbetweentheadsorbentandtheadsorbatesismainlybasedonhydrophobicinteraction.

简介：一种amphiphilic功能的单体被选择修改polyacrylamide(PAM)或部分hydrolyzedpolyacrylamide(HPAM)。修改polyacrylamide(HM-PAM)的相对性质并且部分修改了象旋转的半径那样的hydrolyzedpolyacrylamide(HM-HPAM)(Rg),水动力学半径(RH),和光线的分发功能(RDF)是学习了与从1%～4%改变修改单体的数量发现在聚合物链和内在的粘性的微观结构之间的内在的关系。当修改单体的百分比是2%并且当时，有更强壮的盐忍耐时，模拟结果证明与HPAM相比，HM-HPAM在增加粘性有更好的表演修改单体是4%。而且，复杂的氢结合的网络与光线的分发函数(RDF)的分析被揭示，对关联函数被用来调查Na的扩散性在COO的+和碳原子组。

简介：ThecatalyticreactionofNOwithCOanddecompositionofNOovermetalmodifiedACFswereinvestigatedandcomparedwithothercarrierssupportedcatalysts.ItisdemonstratedthatPd/ACFandPd/Cu/ACFhavehighcatalyticactivityforthereactionofNO/CO,whilePt/ACF.Pt/Cu/ACFandCo/Cu/ACFhaveveryIowcatalyticactivityinsimilarcircumstance.Pd-modifiedACFpossesseshighcatalyticdecompositionofNOat300℃.Pd/CBandPd/GACpresentgoodcatalyticdecompositionabilityforNOonlyatlowflowrate.Pd/G,Pd/ZMSandPd/Ahowever,donotshowanycatalyticactivityforNOdecompositionevenat400℃.Catalytictemperature,NOflowrateandloadingofmetalcomponentsaffectthedecompositionrateofNO.ThecoexistenceofCuwithPdonCu/Pd/ACFleadstocrystallineofpalladiumtomoreunperfectedsoastothatincreasethecatalyticactivity.

简介：Thefructosemodifiedchitosanmicrocarries(CMs)werepreparedbythereactionofglutaraldehydewithfructose-modifiedchitosan.Variousfactorsthatinfluencethepreparationwerestudiedandthereactionconditionswereoptimized.MorphologyofrathepatocytesculturedonCMswasobservedusingphasecontrastmicroscopeandscanningelectronmicroscope,andthemetabolicactivitiesweremeasured.RathepatocytesculturedonCMsretainedthesphericalshapeastheyhaveinvivoandhadhighmetabolicactivities.FructosecanenhancethemetabolicactivityofhepatocytesandthemodifiedCMsarepromisingscaffoldforhepatocytesattachment.

简介：Polymernanoparticleswerepreparedinthemethylmethacrylate(MMA)/butylmethacrylate(BA)emulsioncopolymerizationprocessbyamodifiedmicroemulsioncopolymerizationmethod.2-Hydroxyethylmethacrylate(HEMA),acrylate(AA)andmethylacrylate(MAA)wereusedasreactivecosurfactants.Withthisprocesshighpolymer:surfactantweightratios(40:1orgreater),relativelyconcentrated(～30wt.%)latexesandsmall(～60nm)particlediameterswereobtained.PropertiesofthelatexeswerecharacterizedbyTEM,DSC,dynamiclightscattering,andIRspectroscopy.

简介：StructuresofaseriesofactivatedcarbonfibersweremodifiedbyimpregnatingthemwithorganicandinorganicmaterialssuchasMethyleneblue(Mb)、p-nitrophenol(PNP)、NaClorbyoxidizingwithKMnO4orHNO3.Theinfluenceofporefillingorchemicaltreatmentontheirxenonadsorptionpropertieswasstudied.TheexperimentalresultsshowthatMbandPNPfillingofactivatedcarbonfibersresultinthedecreaseofxenonadsorptioncapacitiesofthesetreatedACFs,whichisduetothedecreaseoftheirsurfaceareaandmicro-porevolume.However,theadsorptioncapacityincreasesgreatlywithoxidizingtreatmentofactivatedcarbonfibersby7mol/LHNO3.

简介：Wepresentherethedevelopmentofcholesterol(Chol)-modifieddendrimersystemfortargetedchemotherapyoffolate(FA)receptor-expressingcancercells.Inourstudy,poly(amidoamine)(PAMAM)dendrimersofgeneration5(G5)werefunctionalizedstepby-stepwithChol,fluoresceinisothiocyanate(FI),andFAviaapoly(ethyleneglycol)(PEG)spacer(PEG-FA),andthenacetamidetoshieldtheirremainingsurfaceamines.ThesynthesizedG5.NHAc-Chol-FI-PEG-FA(forshort,G5-CFPF)dendrimerswereutilizedtoencapsulate10-hydroxycamptothecin(HCP),ahydrophobicanticancerdrug.WefindthateachG5-CFPFdendrimercanencapsulate13.8HCPmolecules.ThecomplexesshowaslowerreleaseprofilesofHCPinapH-dependentmannerthanthecontrolcomplexesformedusingthesamedendrimerswithoutCholunderthesameconditions.ThankstothetargetingroleplayedbyFA,thecomplexesdisplayaspecificinhibitionefficacytoFAreceptor-expressingcervicalcancercells.ThedesignedChol-modifieddendrimersmaybeadoptedasapromisingcarrierforapplicationintargetedcancertherapy.

简介：变形癌症房间的俘获和察觉为恶意的瘤的诊断和治疗是关键的。这里，我们报导folic酸(FA)的使用poly修改了electrospun(乙烯基白酒)(PVA)为癌症房间俘获应用的/polyethyleneimine(PEI)nanofibers。由glutaraldehyde蒸汽的ElectrospunPVA/PEInanofiberscrosslinked与FA被修改经由一poly(乙烯乙二醇)(木钉)分隔符，由纤维表面PEI胺的acetylation列在后面。形成的修改FA的nanofibers很好被描绘。electrospunPVA/PEInanofibers的形态学尽管有表面修正光滑、一致。另外，修改FA的nanofibers显示由溶血证实了的好hemocompatibility试金。重要地，发达修改FA的nanofibers能明确地捕获癌症房间overexpressingFA受体，它被数试金和质的共焦的显微镜学分析的量的房间验证。发达修改FA的PVA/PEInanofibers可以被用于为癌症诊断应用程序捕获传播肿瘤房间。

简介：Antibacterialpoly(D,L-lactide)(PDLLA)fibrousmembranesweredevelopedviaelectrospinning,followedbysurfacemodificationwhichinvolvedplasmapretreatment,UV-inducedgraftcopolymerizationof4-vinylpyridine(4VP)andquaternizationofthegraftedpyridinegroupswithhexylbromide.ThesuccessofmodificationwithquatemizedpyridiniumgroupsonthePDLLAfibrousmembraneswasascertainedbyX-rayphotoelectronspectroscopy(XPS).TheantibacterialactivitiesofthesemembraneswereassessedagainstGram-positiveStaphylococcusaureus(S.aureus)andGram-negativeEscherichiacoli(E.coli).ThePDLLAfibrousmembranesmodifiedwithquaternizedpyridiniumgroupsshowedantibacterialefficiencyagainstbothbacteriaashighas99.999%.Theresultsdemonstratedthattheantibacterialactivitywasbasedontheinteractionofthepositivechargeofpyridiniumgroupandnegativelychargedcellmembraneofbacteria,resultinginlossofmembranepermeabilityandcellleakage.