简介:AbstractCoronavirus disease 2019 (COVID-19) is a newly emerged infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The number of COVID-19 cases is continuously increasing and no effective drugs or vaccines are currently available. Accurate and efficient diagnostic testing methods are desperately needed for the detection of SARS-CoV-2 and antiviral antibodies in infected individuals. Various assay techniques, including nucleic acid tests [eg, polymerase chain reaction (PCR), reverse transcription-PCR, real-time loop-mediated isothermal amplification, and CRISPR-Cas-based detection], serological tests [eg, immunoglobulin (Ig)A, IgM/G], imaging tests (eg, computed tomography and positron-emission tomography), and nanoparticle-based detections have been reported for COVID-19 diagnosis. This review aims to present the current diagnostic tools for SARS-CoV-2 and their performance characteristics to inform the appropriate selection of diagnostic and surveillance technologies at optimal testing times. We also describe the advantages of detection using combined nucleic acid and imaging tests, or serological testing and point-of-care diagnostics. Developing reliable protein biomarkers targeting the conserved proteins of SARS-CoV-2 rather than IgA, IgM, or IgG would be useful to manage SARS-CoV-2.
简介:2013年7月21到27日,第19届世界美学大会在波兰克拉科夫市亚捷隆大学举行。本届世界美学大会是由国际美学协会赞助,波兰美学学会组织的。会议提出了一系列主题:第一,美学---观察与校正;第二,艺术中的古今变化;第三,实践中的美学:宗教、伦理、教育、政治、法律、经济、贸易、时尚、运动、日常生活等领域中的审美要素;第四,美学与自然:进化论、生态学、后人类主义;第五,身体美学:体与知;第六,艺术与科学;第七,美学与艺术中的技术尤其是生物技术;第八,建筑与都市空间;第九,美学中的文化与跨文化研究;第十,过渡地带:文化、美学与艺术中的断裂、变革与变形。来自48个国家的约460位学者参与发言。
简介: 真是不敢相信,从默里上次给他打电话指派任务距今才不过区区七天!七天前,他不知道"三角形"是个什么东西,不认识玛格丽特·蒙托娅,也不知道马丁·布鲁贝克是谁.七天前,他的搭档也没在这该死的病床上躺着,是的,那该死的医院的病床!是杜害了他.……
简介:AbstractSince the outbreak of the novel coronavirus in Wuhan, China, as obstetricians, we also face great challenges. We need to identify pregnant patients with 2019 coronavirus disease infection timely, and give them appropriate treatment in order to obtain a good maternal and infant prognosis. Here, we would like to share a case and provide some suggestions on how to screen, diagnose and treat pregnant women with 2019 coronavirus disease infection during the outbreak.