简介：AbstractMost of the medical and nonmedical research labs, all around the world, are racing against time to produce an effective vaccine or an antiviral medicine for coronavirus disease 2019 (COVID-19). Conventional medicines and novel nano-materials including chemical and herbal-based compounds are all into positive trials toward coronaviruses and other pandemic infections. Among them, natural immune boosters have attracted physicians because of their longevity and reliability for fewer side effects. This is a review article with a detailed picture of an unexplored antiviral source with maximum potency in curing viral infections. Cyanobacteriae have been known for centuries and are rich in secondary metabolites of proteins, biopeptides, and polysaccharides for prominent antiviral action against chest infections. But detailed exploratory research is required to purify, scale-up, and commercialize the pharmacologically active agents from these drug reserves.

简介：Radiointerference(RI),asanaftereffectofcoronadischarge,isanimportantresearchtopicinthefieldofelectromagneticcompatibility,whereexcitationfunctionisappliedbroadlytothepredictionofRIlevel.ThispaperpresentsthetheoryofexcitationfunctionmethodusedintheRIlevelprediction.Then,somepracticalproblemsrelatedtothismethodarediscussed.Thepropagationprocedureofcoronacurrentissolvedbythephase-modaltransformation,andtheimpedancematrixofmultitransmissionlinesiscalculatedbyadoublelogarithmicapproximatemodelofCarson'sGround-Returnimpedance.Atthesametime,inordertocalculatetheRIlevelwhentotallinecoronaisassumed,ananalyticalformulaisdeducedforintegraloperation.Basedontheabovesolutions,analgorithmispresentedandappliedtothepredictionofRIlevelofapracticaloverheadtransmissionline.Comparisonofpredictionandmeasurementresultsindicatesthatthealgorithmproposedinthispaperiseffectiveandfeasible.

简介：Anexperimentandanalysisonremovalofgaseousbenzenebypulsecoronainducedplasmaispresentedinthisarticle.Importantparameterseffectingremovalefficiencyhavebeeninvestigated,suchaspulsepeakvoltage,pulsefrequency,gasinletconcentration,gasflowrateandreactortemperature.Theresultshowsthattheremovalefficiencyincreaseswiththeincreaseinpulsepeakvoltage,pulsefrequencyandreactortemperature,butdecreasesintheriseofgasinletconcentrationandgasflowrate.OntheconditionofVp=36kV,f=80Hz,C=1440mg/m^3andQ=640ml/min,thelargestremovalefficiencyis98%.Finally,thereactedproductsarequalitativelyanalysedandthereactionprocessesarededucedincombinationwithplasma-chemistrytheory.

简介：继去年9月的‘樱花’病毒之后前些日子又有一个叫“正版骗子”的病毒在网络上流传开采．和“樱花”病毒相同．该病毒也是拿反病毒厂商的杀毒软件开涮．不但会终止这几款杀毒软件．还会弹出具有迷惑性语言的对话框，给国内杀毒软件的正版用户开了一个大大的玩笑。

简介：在xenotropic之间的潜在的协会鼠科的白血球过多症自从2006，病毒相关的gammaretrovirus(XMRV)和前列腺癌症(PCa)被记录了。查明这个协会是否是原因的，为推进我们PCa的生物机制的理解是重要的。总结可得到的信息在上流行病学并且协会的实验室调查结果，我们进行了PubMed电子数据库的文学搜索(从2006年3月到2011年2月)那检验了在XMRV和PCa之间的协会识别相关出版研究。尽管几研究显示出在XMRV和PCa之间的积极协会，更最近的研究没支持这个结论。积极调查结果可能由于人的样品的污染。进一步的研究被需要澄清这个协会。

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简介：LastWednesday,AgricultureSecretaryAnnVenemanannouncedthefirstcaseofmadcowdiseaseintheUnitedStates.Atestseemedtoshowbovinespongiformencephalopathy,orB-S-E.inacowfromWashingtonstate.Thenextday,alaboratoryinWaybridge,England,Confirmed(证实）thecase。

简介：印射响应许多ligands和房间刺激涉及大量的细胞的小径和功能的家族asestransduce信号。MAPK的异常或不恰当的功能现在在从癌症到煽动性的疾病到肥胖和糖尿病的疾病被识别了。在许多房间类型，MAPKERK1/2被连接到细胞增殖。因为在地岬和B-Raf的变化，能激活ERK1/2串联，在许多人的肿瘤被发现，ERK1/2被认为在一些癌症起一个作用。发信号的反常ERK1/2也在polycystic肾疾病被发现了，并且象cardio-facio-cutaneous症候群那样的严肃的发展混乱在ERK1/2串联的部件从变化产生。ERK1/2在区分得好的房间是必要的并且在神经原并且在上皮的极性的维护被连接了到长期的potentiation。另外，ERK1/2为在胰腺的贝它房间的胰岛素基因抄写是重要的，它响应传播葡萄糖的增加生产胰岛素在有机体允许有效葡萄糖利用和存储。导致或镇压的营养素和荷尔蒙胰岛素分泌物以在贝它房间上反映能分泌的需求的一种方式激活或禁止ERK1/2。在这和另外的规章的小径的骚乱可以导致对某些人的混乱的病原学的ERK1/2的贡献。

简介：Asthmadevelopsinaboutoneadultperthousandpopulationperyear,andepidemiologicalstudiesindicatethatabout10%ofcasescanbeattributedtoexposuresatwork.However,occupationalasthmaisidentifiedlesscommonlythanthisinclinicalpractice;anincidenceof800-1000casesperyearisestimatedbytheUKSurveillanceofWork-RelatedandOccupationalRespiratoryDiseasescheme.Occupationalasthmaiseasilymissedbecause,apartfromitsassociationwithwork,

简介：HeartdiseaseistheleadingkillerofAmericans.Butitkillsmorewomenthanmen.TheAmericanHeartAssociationsaysheartdiseaseandothercardiovascular(心血管的)disorderskillaboutfivehundredthousandwomenayear.Thatismorethanthenextsevencausesofdeathcombined.

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简介：Theinvestigationofelectrochromiceffectofcorona-polednonlinearopticalpolymerfilmsisaneffectivemethodfortheestimationofpolinglevelandtheselectionofpolingconditions.ThepolingelectricfieldEpandorientationalorderparameterΦ,whicharetheimportantparameterstopredictd33ofpoledfilms,canbecalculatedbyasimpleoperationfromthenumberofredshiftofchargetransferabsorptionband.Thecalculatedresultsareingoodagreementwiththeexperimentaldata.

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简介：Inthiswork,wesimulatenumericallythethermaleffectsinnitrogenatatmosphericpressurecausedbyanegativecoronaDCdischargeoflowcurrent.Amathematicalfunctionthatsimulatestheinjectionofthethermaltransferingasisproposed.Thesimulateddischargeisofanegativepointtoplanemasstype,withaninterelectrodedistanceof12mmandasymmetryabouttheaxisofdischarge.Thespatialandtemporalevolutionofneutralsisanalyzedbasedupontheequationsofcontinuity,momentumandenergyinacylindricalgeometry.Forthegeometryofthesystem,theFCT(fluxcorrectedtransport)procedurewasadopted.

简介：AbstractBackground:The prevalence rates of freezing of gait (FOG) in Parkinson’s disease (PD) vary widely, ranging from 14.0 to 55.1%. Our aim is to calculate the overall prevalence of FOG in all PD patients with different disease durations and severities.Methods:Using Medline/PubMed/Embase, we carried out a systematic literature search for studies reporting the PD and clinically relevant FOG.Results:After primary screening, a total of 35 studies were identified and further analyzed for inclusion into the analysis, and 29 studies fulfilled the quality criteria and included in this meta-analysis. The overall prevalence of FOG in PD was 39.9% (95% CI 35.3-44.5%). The FOG identified by the freezing of gait questionnaire item 3 may be more prevalent (43.8%, 95% CI 38.5-49.1%) than the FOG identified by the Unified Parkinson’s Disease Rating Scale item 14 (36.0%, 95% CI 29.0-43.1%). Disease duration and severity are both the clinical features associated with the FOG. The highest FOG prevalence rate in PD patients was seen in patients with disease durations ≥ 10 years, at 70.8%, followed that of PD patients with disease durations ≥ 5 years (53.3%), and PD patients with disease durations < 5 years (22.4%). FOG presented in 28.4% of PD patients with Hoehn and Yahr staging (H&Y) score ≤ 2.5, and in 68.4% of PD patients with H&Y score ≥ 2.5.Conclusion:This meta-analysis confirms that the prevalence of FOG in PD is considerable, and highlights the need for accurate identification of FOG in PD.

简介：Liverinjuryisacharacteristicfeatureofhumanimmunodeficiencyvirus(HIV)infection,whichisthesecondmostcommoncauseofmortalityinHIV-infectedpatients.NowitisrecognizedthatliverplaysakeyroleinHIVinfectionpathogenesis.Antiretroviraltherapy(ART),whichsuppressesHIVinfectioninpermissiveimmunecells,islesseffectiveinhepatocytes,therebymakingthesecellsasilentreservoirofHIVinfection.InadditiontodirecthepatotoxiceffectsofHIV,certainARTtreatmentmodalitiesprovidehepatotoxiceffects.TheexactmechanismsofHIV-triggeredchronichepatitisprogressionarenotelucidated,buttheliverisadverselyaffectedbyHIV-infectionandlivercellsareprominentlyinvolvedinHIV-elicitedinjury.Theseeffectsarepotentiatedbysecondhitslikealcohol.Here,wewillfocusontheincidenceofHIV,clinicalevidenceofHIVrelatedliverdamage,interactionsbetweenHIVandlivercellsandtheroleofalcoholandco-infectionwithhepatotropicvirusesinliverinflammationandfibrosisprogression.

简介：Witheffectivecontrolandpreventionmeasures,thenumberofHIVcarriersandAIDSpatientsinChinacouldbelimitedto1.5millionin2010,saidChenXianyi,aseniorofficialwiththeMinistryofHealth.Butwithoutsuchsteps,therecouldbemorethan10million,Chenwarned.Chenmadetheremar...

简介：<正>Manyvirusesestablishlife-longinfectionsintheirnaturalhostwithfewifanyclinicalmanifestations.Therelationshipbetweenvirusandhostisadynamicprocessinwhichthevirushasevolvedthemeanstocoexistbyreducingitsvisibility,whilethehostimmunesystemattemptstosuppressandeliminateinfectionwithoutdamagetoitself.Wearenowbeginningtounderstandthatvirusescanemployavarietyofstrategiestoevadehostimmuneresponses.TheseincludeescapefromTcellrecognition,resistanceto

简介：AbstractThis paper reviews the current epidemics of human immunodeficiency virus (HIV) infection in China, particularly the globally available prevention strategies developed and implemented. This review focuses on HIV prevention measures in general, such as education, testing, and counseling and in specific responses to transmission modes, such as blood safety, harm reduction for people who inject drugs, and condom promotion to reduce sexual transmission. We also assess newly developed prevention measures, such as prevention treatment, pre-exposure prophylaxis, post-exposure prophylaxis, male circumcision, and promising potential future preventions, including microbicides and vaccines. Based on this assessment, we provide recommendations for their implementation in China. We conclude that there is no magic bullet for HIV prevention, particularly sexual transmission of the disease, but only a combination of these prevention strategies can control the HIV epidemic.