简介：

简介：Acockcrowsinthemorningtotellustorise,Andhewholikeslatewillneverbewise.Forearlytobedandearlytorise,Isthewaytobehealthyandwealthyandwise.

简介：

简介：

简介：

简介：AbstractPreeclampsia is a progressive, multi-system disorder of pregnancy associated with morbidity and mortality on both the mother and the fetus. Currently, research is directed at identifying early biomarkers of preeclampsia in order to predict its occurrence. This is important because it helps understand the pathophysiology of the disease, and thus, promises new treatment modalities. Although a clear understanding of the pathogenesis of PE remains elusive, the currently most accepted theory suggests a two-stage process. The first stage results in inadequate remodeling of the spiral arteries and leads to the second stage, whereby the clinical features of the syndrome are featured. In this review, we summarize the modalities that have been studies so far to predict preeclampsia. The use of uterine artery Doppler and several other biomarkers such as vitamin D, soluble fms-like tyrosine kinase 1/placental growth factor (sFLT1/PlGF) ratio, soluble endoglin, and a subset of T-lymphocytes has shown promising results. We are still at early stages in this advance, and no clear recommendations have been made about their clinical use to date. Further studies are still needed to improve screening strategies and evaluate the cost-effectiveness of any intervention.

简介：

简介：Researchongeomagneticreversalchronologyhasestablishedtheexistenceoftwosuperchrons,oneduringtheCretaceousandtheother(Kiaman)duringtheLatePaleozoic.Overthepastfewyears,wehaveperformedseveralmagnetostratigraphicstudiesonEarlyPaleozoic(CambrianandOrdovician)sedimentarysequencesfromSiberia.OurresultsshowhighmagneticreversalfrequenciesduringtheMiddleCambrian.Incontrast,severalrecordsshowtheoccurrenceofa-20MyrlongreversedpolarityintervalintheLowerandMiddleOrdovician,suggestingthepresenceofathirdsuperchron.Weproposetogivethenameof“Moyero”tothisnewsuperchron;thisnameisattributedtotheSiberiansectionwhichfirstyieldedacompleterecordofthisreversedpolarityinterval.

简介：1.TheState:GeneralConsiderationsScholarshavelongbeinginterestedinthestateandtherunningofit.Amongthem,therewerephilosophers,historians,sociologistsandanthropologists.WemaygoasfarbackastoConfuciusandLaoTze,ortotheGreekphilosophersPlatoandAristotle1,andifwewanttostayclosertoourtime,wecanmentiontheItalianpoliticalscientistMachiavelli,whowroteinthe16thcenturyIlPrincipe(ThePrince),

简介：通过地震预报的自然、社会的属性的分析，在地震预报的自然、社会的属性(早警告)之间的关系有是天赋地震预报归因的discussed.Regarding，它仅仅试图预报大小，地点和出现基于观察数据和相关理论的aualysis未来地震预定并且考虑seismogeny和地震generation.I的现在的理解

简介：TheauthorshavedetailedlyandsystematicallystudiedthecarbonisotopiccompositionofEarlyProterozoiccarbonaterocks.SampleswhicharealldolomicriteweretakenfromtheJianancun,DaguandongandHuaiyincunFormationsoftheHutuoGroupinWutaiCountyShanxiProvince,NorthChina.Atotalof209sampleswereanalysedfortheircarbonisotopecompositions,andthemeansamplingintervalwas6.9m.Carbonisotopeanalysisclearlyshowsδ13CshiftsattheboundarybetweentheJian’ancunFormationandDaguandongFormationandneartheboundarybetweentheDaguandongFormationandHuaiyincunFormation.LikecarbonisotopeshiftsattheCretaceous-Tertiary,Permian-TriassicandPrecambrian-Cambrianboundaries,thediscoveryofδ13CshiftsintheEarlyProterozoichasimportantsignificanceinfurtherstudiesonEarlyProterozoicbioticevolution,regionalandglobalstratigraphiccorrelation,andcarbongeochemicalcycles.

简介：

简介：Earlydiagnosisandtreatmentisthekeytoimprovingtheprognosisofgastriccancer.Thepastdecadeshavewitnessedtherapidadvancesinthediagnosisandmanagementofearlygastriccancer(EGC):endoscopyhasplayedanincreasinglyimportantrole,whereaslaparoscopictechniqueshavealsobeenintroducedforEGCtreatment.InChina,the

简介：

简介：Afterreviewingcurrentresearchesonearlywarning,itisfoundthat'bad'dataofsomesystemsisnoteasytoobtain,whichmakesmethodsproposedbytheseresearchesunsuitableformonitoredsystems.AninteractiveearlywarningtechniquebasedonSVDD(supportvectordatadescription)isproposedtoadopt'good'dataassamplestoovercomethedifficultyinobtainingthe'bad'data.Theprocessconsistsoftwoparts:(1)Ahypersphereisfittedon'good'datausingSVDD.Ifthedataobjectareoutsidethehypersphere,itwouldbetakenas'suspicious';(2)Agroupofexpertswoulddecidewhetherthesuspiciousdatais'bad'or'good',earlywarningmessageswouldbeissuedaccordingtothedecisions.Andthedetailedprocessofimplementationisproposed.Atlast,anexperimentbasedondataofamacroeconomicsystemisconductedtoverifytheproposedtechnique.

简介：Objective:Toevaluatetheeffectofosteoporosisonfracturehealingthroughobservingthehistomorphologicalchanges,bonemineraldensityofcallusandexpressionanddistributionoftransforminggrowthfactorbeta1(TGF-β1),basicfibroblastgrowthfactor(bFGF)andbonemorphogeneticprotein-2(BMP-2)inovariectomizedrats.Methods:SixtyfemaleSprague-Dawleyrats(aged12weeksandweighing235gonaverage)wererandomlydividedintoanovariectomized(OVX)group(n=30)andasham-operated(SO)group(n=30).OvariectomywasperformedintheOVXratsandsameincisionwasmadeintheSOrats.Threemonthslater,fractureoffemoralshaftwasmadeonalltherats.Thentheywerekilledatdifferenttimepoints.Callusformationwasobservedwithhistologicalandimmunohistochemicalmethods.Results:AreductionincallusandbonemineraldensityinthehealingfemurandadecreaseofosteoblastsexpressingTGF-β1nearthebonetrabeculawereobservedintheOVXrats3-4weeksafterfracture.HistomorphologicalanalysisrevealedahighercontentofsoftcallusintheOVXratsthanthatintheSOrats.ImmunohistochemistryresultsshowedthatnoremarkabledifferenceinexpressionanddistributionofBMP-2andbFGFbetweentheOVXandSOgroupswasfound.Conclusions:Osteoporosisinfluencesthequantityandqualityofcallusduringtheearlyperiodoffracturehealing.TheeffectofosteoporosisonfracturehealinghasnorelationshipwiththeexpressionofBMP-2orbFGF.ThedecreasedexpressionofTGF-β1inosteoblastsmaycauseadecreaseinqualityoffacturehealingafterosteoporosis.

简介：Alongwiththeringofthemillenniumbell,thehumansocietyhasenteredanewcentury,andChina’snationalrejuvenationhascomeintoanewstage.Undoubtedly,thecomingtenyearsareofgreatsignificancebecausetheywillserveasalinkbetweenthepastandthefuture.Duringthisperiod,furtherdeepeningofrevolutioninscienceandtechnologyrepresentedbyinformationtechnologyandof

简介：精子是导出把父亲的单倍体染色体送到卵母细胞的一种高度专业化的房间类型。渐成说，或基因规章，精子的性质和机制在父亲的染色体的准备帮助贡献胚胎开始和接合子的染色体。许多最近的研究在精子处理了改变的渐成说过程的问题。这评论评估DNA损坏，染色体非整倍性，减少的端粒长度，中心体的畸形性，印错误的genomic，改变的mRNA侧面，并且在胚胎开始上的在授精和观察效果以前的在精子的反常原子包装的当前的理解。注意也被给了在人与改变的渐成说机制理解精子的内在的病原学。

简介：Inordertosolvetheproblemofearlyestimationofmoderatelystrongaftershockdurationtimeinanearthquakesequence,thisstudyhasbeenconducted.First,thedefinitionofthestrongaftershockhasbeengiven.Itispointedoutthatthereisadifferenceinthestrongaftershockdurationtimebetweenthemainshocktypesequenceandthestrongearthquakeswarmsequence.Afterdividingthethreecases,i.e.,astrongaftershockdurationtimelargerthan1day,smallerthan1day,andnostrongaftershockoccurredinamainshocktypesequencebyusingthepatternrecognitionmethod,wegavetheroughcorrelationrelationbetweenstrongaftershockdurationtimeandfirstlargeshockmagnitudefortwotypesofsequences.Finally,thejudgmentindexandmethodofestimatingstrongaftershockdurationtimesfordifferentsequencetypeshavebeengiven.

简介：这份报纸早为地震评估不同特征警告。在大小，震中距离和计算参数之间的可伸缩的关系从USGS从地震事件数据被导出。标准STA/LTA方法被增加二个新参数在P波浪的发作前消除尖铁类型噪音和小pulsetype噪音的效果修改。在P波浪的察觉以后，算法从P波浪的开始的3秒提取12种参数。这些参数的然后逐步的回归分析被执行估计震央的距离和大小。六个不同参数被选择估计震央的距离，和为所有419估计的中部的错误是16.5km。四个参数最佳地被联合估计大小，并且为所有事件的吝啬的错误是0.0个大小单位，与0.5的标准差。基于评价结果，最后，另外的工作被建议改进结果的精确性。