简介：金陵药业“脉络宁”产品的生产．集联动化管道化和自动化等高科技生产技术于一体，实现了全过程自动化，体现了现代中药生产的先进水平。早在20世纪90年代，根据国家GAP要求，金陵药业与中国药科大学，

简介：金陵药业“脉络宁”产品的生产，集联动化、管道化和自动化等高科技生产技术于一体，实现了全过程自动化，体现了现代中药生产的先进水平。早在20世纪90年代，根据国家GAP要求，金陵药业与中国药科大学、中科院南京土壤研究所等单位合作，投入巨资，分别在云南思茅、河南封丘、浙江磐安和广西鹿寨等地建立了中药材种植基地。这既满足了“脉络宁”规模化生产的需求，又保证了药材供应的稳定、纯天然、无污染，从源头上控制“脉络宁”产品质量，同时也为制定和推行“脉络宁”产品指纹图谱的金标准创造了条件。

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简介：Duringperipheralnervetranspositionrepair,ifthediameterdifferencebetweentransposednervesislargeormultipledistalnervesmustberepairedatthesametime,traditionalepineurialneurorrhaphyhastheproblemofhightensionatthesuturesite,whichmayevenleadtothefailureofnervesuture.Weinvestigatedwhetherasmallgapbio-sleevesuturewithdifferentinnerdiametersatbothendscanbeusedtorepaira2-mmtibialnervedefectbyproximaltranspositionofthecommonperonealnerveinratsandcomparedtheresultswiththerepairseenafterepineurialneurorrhaphy.Threemonthsaftersurgery,neurologicalfunction,nerveregeneration,andrecoveryofnerveinnervationmusclewereassessedusingthetibialnervefunctionindex,neuroelectrophysiologicaltesting,musclebiomechanicsandwetweightmeasurement,osmicacidstaining,andhematoxylin-eosinstaining.Therewasnoobviousinflammatoryreactionandneuromaformationinthetibialnerveafterrepairbythesmallgapbio-sleevesuturewithdifferentinnerdiametersatbothends.Theconductionvelocity,musclestrength,wetmuscleweight,cross-sectionalareaofmusclefibers,andthenumberofnewmyelinatednervefibersinthebiosleevesuturegroupweresimilartothoseintheepineurialneurorrhaphygroup.Ourfindingsindicatethatsmallgapbio-sleevesuturewithdifferentinnerdiametersatbothendscanachievesurgicalsuturebetweennervesofdifferentdiametersandpromoteregenerationandfunctionalrecoveryofinjuredperipheralnerves.

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简介：Themostimportantriskfactorforstrokeandneurodegenerationisaging.Infact,survivalafterstrokediminisheslargelywithaging.Infact,recoveryafterbrainarteryocclusionisdramaticallyworsenedbyaging,evennormalagingisassociatedwithneurondamageandcognitivedecline.Mechanismsinvolvedinaging-related,cognitivedeclineandsusceptibilitytoneurondamageinstrokeandneurodegenerationarelargelyunknown.Oneofthemostimportant

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简介：Thecurrentstudydemonstratedthatinjuryofthespinalcordlateralfuniculusoccursinlivercirrhosis.Thisstudysoughttocomparethemorphologyofthethoracicandlumbarcord,theexpressionoffunctionalproteins,andchangesinvesselsbetweenlivercirrhosisandnon-cirrhosiscorpses.Resultsshowedthatinthelivercirrhosisgroup,thehepaticveinexpanded,thegastrointestinaltractwasfullofcoagulatedblood,blood-stasiswaseasilyseenintheveniplexofthevertebralcanalandthelumbarspinalcord,andthecellbodiesoftheanteriorhorninthethoracicandlumbarcordweresmallerthanthoseinnon-cirrhosiscorpses.Inaddition,nervecellsshrank,Nisslbodieswereconcentratedwithobscurednuclei,andneurofilamentandsynapsincontainingcellbodiesoftheanteriorhornandwhitematterdecreasedinthelivercirrhosisgroup.Theseexperimentalfindingsindicatethatabnormalcirculationofthespinalcord,resultingfromhemodynamicchangeofcirrhoticportalhypertension,maybethemostsignificantcauseofhepaticmyelopathy.