简介：

简介：Microporoustitaniumcarbidecoatingwassuccessfullysynthesizedonmedicalgradetitaniumalloybyusingsequentialcarburization.Changesinthesurfacemorphologyoftitaniumalloyoccasionedbysequentialcarburizationwerecharacterizedandthewettabilitycharacteristicswerequantified.Furthermore,thedispersionforceswerecalculatedanddiscussed.Theresultsindicatethatsequentialcarburizationisaneffectivewaytomodifythewettabilityoftitaniumalloy.Afterthecarburizationthesurfacedispersionforceoftitaniumalloyincreasedfrom76.5×10-3J·m-2to105.5×10-3J·m-2,withanenhancementof37.9%.Meanwhilethecontactangleoftitaniumalloydecreasedfrom83°to71.5°,indicatingasignificantimprovementofwettability,whichismuchclosertotheoptimalwatercontactangleforcelladhesionof70°.

简介：

简介：Inthisstudyalumbarspinalfusionanimalmodelisestablishedtoassesstheeffectofspinalfusioncage,andexploretheminimumarearatiooftitaniumcagesectiontovertebralsectionthatensuresbonehealingandbiomechanicalproperty.Lumbarcorpectomywasconductedbyposterolateralapproachwithtitaniumcageimplantationcombinedwithplatefixation.Titaniumcageswiththesamelengthbutdifferentdiameterswereused.Afterimplantationoftitaniumcages,theprogressofbonehealingwasobservedandthebonebiomechanicalpropertiesweremeasured,includingdeformationanddisplacementinaxialcompression,flexion,extension,andlateralbendingmotion.Thefactorsaffectingtheinvivogrowthofspinesupportingbodywereanalyzed.Theresultsshowthatthearearatiooftitaniumcagesectiontovertebralsectionshouldreach1/2toensurethebonehealing,sufficientboneintensityandbiomechanicalproperties.Somebonehealingindicators,suchasBMP,suggestthatthereisarelationshipbetweenthepeaktimeandthepeakvalueofboneformationandmetabolismmarkersandthebonehealingstrength.