Preliminary Survey on the Prevalence Rate of Hypertension in Patients with Dilated Cardiomyopathy

(整期优先)网络出版时间:2008-04-14
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ObjectivesToinvestigatetheprevalenceofhypertensionanditsprimaryriskfactorsinpatientswithdilatedcardiomyopathy(DCM).MethodsThreehundredandsixty-twopatientswithDCM(DCMgroup)and401age-matchedresidents(controlgroup)wereenrolledrandomlyinthestudy,thehypertensiveprevalenceratewerecalculatedrespectivelyinthetwogroupsandwerecomparedwitheachother;thepatientsintheDCMgroupwerepidedintotwosubgroups(hypertensionsubgroupandnon-hypertensionsubgroup)accordingtowhetherthepatientshavehypertension;theclinicaldatarelatedtobloodpressurewascomparedbetweenthetwosubgroups.ResultsTheprevalenceofhypertensioninDCMgroupwassignificantlyhigherthanthatinthecontrolgroup(32.8%vs.20.1%,P<0.01);Therewerenosignificantdifferencesontheage,gender,occupationandleftventricularejectionfraction(LVEF)betweenthetwosubgroups,butthemeanheartrateandthepercentageofpatientswhohadfamilyhistoryofhypertensionweresignificantlyhigherinthehypertensionsubgroupthanthatinthenon-hypertensionsubgroup(P<0.05andP<0.01).ConclusionsTheprevalenceofhypertensioninpatientswithDCMwashigh;TheincreasedactivityofsympatheticnervoussystemandthehypertensivegeneticfactormaybethemainriskfactorsofhypertensioninpatientswithDCM.