Activation-Induced Cell Death in T Cells and Autoimmunity

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摘要 Activation-inducedcelldeath(AICD),whichresultsfromtheinteractionbetweenFasandFasligand,isresponsibleformaintainingtolerancetoself-antigen.AdefectinAICDmayleadtodevelopmentofautoimmunity.Duringthelastseveralyears,muchprogresshasbeenmadeinunderstandingthemechanism(s)ofAICDanditspotentialroleinthepathogenesisofautoimmunediseases.Inthisreview,wesummarizethemostrecentprogressontheregulationofthesusceptibilityofTcellstoAICDanditspossibleinvolvementinautoimmunediseases.
机构地区 不详
出版日期 2004年03月13日(中国期刊网平台首次上网日期,不代表论文的发表时间)
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