简介：Objective:ToevaluatetheefficacyandsafetyofintratympanicandsystemicsteroidtherapiesintheinitialtreatmentofSuddenSensorineuralHearingLoss(SSNHL)patients.Methods:AcomprehensivesearchofPubMed,WanfangdatabaseandCNKI(ChinaNationalKnowledgeInfrastructure)wasperformedcoveringtheperiodfromJanuary1990toJuly2014.Ameta-analysiswasconductedafterfilteringbythecriteriaofCochraneCollaboration.Threehundredfiftysixsubjectsinninestudiesallocatedtothegroupofintratympanicsteroidtherapiesand343controlsreceivingsystemicsteroidtherapiesmetthecriteriaformeta-analysis.ThedatawereextractedandanalyzedusingtheRevMan5.3meta-analysissoftware.Results:ThetotaleffectivenessrateinSSNHLpatientsreceivingintratympanicsteroidtherapiesdidnotdifferstatisticallyfrompatientsreceivingsystemictherapies(RR=1.08,95%CI=0.99-1.99,P=0.10),althoughtherateoffullhearingrecoveryinthisgroupdifferedsignificantlyfrompatientsreceivingsystemictherapies(RR=1.29,95%CI=1.00-1.66,P=0.05).Conclusion:LocalsteroidtherapyappearstogeneratehigherrateofcompletehearingrecoverythansystemicsteroidtreatmentasaninitialtreatmentforSSNHL,whichmaybeespeciallyusefulforpatientsinwhomsystemicsteroidsarecontraindicated.

简介：ThemicrostructuralevolutionandVickershardnessmeasurementintheweldingheat-affectedzone(HAZ)ofHD15Ni1MnMoNbCusteelfornuclearpowerstationwereinvestigatedbyGleeble-3180thermalmechanicalsimulator,andthesimulatedHAZcontinuouscoolingtransformationcurves(SH-CCT)weremeasuredsimultaneously.Witht_(8/5)increasingfrom3.75sto15000s,theproductwasobtainedmartensite,bainite,ferriteandpearlite,successively.TheresultofmicrostructureandVickershardnessintheheat-affectedzonewasingoodagreementwiththosemeasuredbySH-CCTdiagramwiththeheatinput16.2kJ/cmasanexampletoweldtheHD15Ni1MnMoNbCusteelpipeusingTIG/SMAW/SAWweldingmethods.

简介：OnApril25,2015,aM_S8.1earthquakeoccurredinNepal.IntheTibetareaofChina,thisearthquakecausedheavycasualtiesanddamagetohousing,roads,communications,otherlifelineengineering,waterconservancyandotherinfrastructure.Thispaperintroducesthebasicsituationoftheearthquake,andbasedontheinvestigationandassessmentofseismicintensity,thedamageofthedisasterareaisanalyzed,andbuildingtypesanddamagetothelifelinesystemsandvariousindustriesaregiven.Throughtheanalysisofthecharacteristicsoftheearthquakedisaster,thispaperpointsouttheexistingproblemsinseismicfortification,andfinallyputsforwardproposalsforthepreventionandcontrolofearthquakegeologicaldisasters,scientificplanningfortherestorationandreconstruction,strengtheningearthquakepreventionanddisasterreductionpropaganda,improvingtheawarenessofearthquakepreparednessintheagriculturalandpastoralareas,strengtheningtheguidanceandsupervisionofhousingconstructioninruralareastoreducethecasualtiesandlosses,andpromotingtheharmoniousdevelopmentofeconomyinTibet.

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简介：Inthisarticle,wetaketheX(5568)asthediquark-antidiquarktypetetraquarkstatewiththespin-parityJ~P=0~+,constructthescalar-diquark-scalar-antidiquarktypecurrent,carryouttheoperatorproductexpansionuptothevacuumcondensatesofdimension-10,andstudythemassandpoleresidueindetailswiththeQCDsumrules.WeobtainthevalueM_X=(5.57±0.12)GeV,whichisconsistentwiththeexperimentaldata.ThepresentpredictionfavorsassigningtheX(5568)tobethescalartetraquarkstate.

简介：精制系统的一个水平地区的三维的热分析模拟为金者半导体材料被进行。考虑几何学包括充满金者在一个圆柱的石英试管放了的一只石墨船。Ar和H2气体混合的流动通过试管被清除。船的狭窄的节被假定暴露于在石英试管外面定位的rf卷生产的经常的热率。这分析的结果在系统关于象熔融的地区，要求的力量和温度坡度的形状那样的各种各样的参数提供必要信息。

简介：Cu2ZnSnS4(CZTS)基于太阳能电池被microelectronic和photonic结构(AMPS-1D)的一个维的太阳能电池模拟软件分析数字地模仿。在模拟使用的设备结构是Al/ZnO:Al/nZn(O，S)/pCZTS/Mo。工作是在ZnO1xSx缓冲区层，它将产出更高的变换效率。由改变S/(S+O)比率x，在CZTS/Zn的传导乐队偏移量(CBO)(O，S)如果比率的完整的范围被考虑，接口能从0.23eV到1.06eV。当时，0.23eV的最佳的CBO能被完成ZnO1xSx缓冲区有S/(S+O)0.6的比率。太阳能电池效率首先与增加硫内容增加然后为x突然地减少>0.6，它由我们的建议的最佳的硫内容x=到达17.55%的最高的价值0.6。我们的结果在处理ZnO1x为高效率CZTS的Sx缓冲区层免职太阳能电池。

简介：AIM:TocomprehensivelyevaluatethepotentialassociationofCOL1A1polymorphismswithhighmyopiabyasystematicreviewandMeta-analysis.METHODS:AllassociationstudiesonCOL1A1andhighmyopiareporteduptoJune10,2014inPubMed,Embase,WebofScience,andtheChineseBiomedicalDatabasewereretrieved.Oddsratios(ORs)and95%confidenceintervals(95%CIs)wereanalyzedforsinglenucleotidepolymorphisms(SNPs)usingfixed-andrandom-effectsmodelsaccordingtobetween-studyheterogeneity.PublicationbiasanalyseswereconductedbyEgger’stest.RESULTS:Atotaloffourstudiesfromreportedpaperswereincludedinthisanalysis.TheMeta-analysesforCOL1A1rs2075555,composedof2304highmyopiapatientsand2272controls,failedtodetectanysignificantassociationwithhighmyopia.Atotalof971casesand649controlsweretestedforCOL1A1rs2269336.TheassociationofCOL1A1rs2269336withhighmyopiawasobservedinrecessivemodel(CCvsCG+GG,P=0.03)andinheterozygousmodel(CGvsGG,P=0.04),butnotinothermodels.CONCLUSION:ThisMeta-analysisshowsthatCOL1A1rs2269336(CCvsCG+GG)affectsindividualsusceptibilitytohighmyopia,whereasthereisnoassociationdetectedbetweenSNPsrs2075555andhighmyopia.Giventhelimitedsamplesize,furtherinvestigationsincludingmoreethnicgroupsarerequiredtovalidatetheassociation.

简介：Thispaperpresentsacoupleddynamicresponseanalysisofamulti-columntension-leg-typefloatingwindturbine(WindStarTLPsystem)undernormaloperationandparkedconditions.Wind-onlyloadcases,wave-onlyloadcasesandcombinedwindandwaveloadcaseswereanalyzedseparatelyfortheWindStarTLPsystemtoidentifythedominantexcitationloads.ComparisonsbetweenanNRELoffshore5-MWbaselinewindturbineinstalledonlandandtheWindStarTLPsystemwereperformed.Statisticsofselectedresponsevariablesinspecifieddesignloadcases(DLCs)wereobtainedandanalyzed.ItisfoundthattheproposedWindStarTLPsystemhassmalldynamicresponsestoenvironmentalloadsanditthushasalmostthesamemeangeneratorpoweroutputunderoperatingconditionsastheland-basedsystem.Thetensionmooringsystemhasasufficientsafetyfactor,andtheminimumtendontensionisalwayspositiveinallselectedDLCs.Theratioofultimateloadofthetowerbasefore-aftbendingmomentfortheWindStarTLPsystemversustheland-basedsystemcanbeashighas1.9inalloftheDLCsconsidered.TheseresultswillhelpelucidatethedynamiccharacteristicsoftheproposedWindStarTLPsystem,identifythedifferenceinloadeffectbetweenitandland-basedsystems,andthusmakerelevantmodificationstotheinitialdesignfortheWindStarTLPsystem.

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简介：微结构和电子横梁的机械描述焊接了伪造Ti-6Al-4V的关节被调查。Microhardness测试显示熔化地区(FZ)的坚硬比影响热的地区(HAZ)和贱金属的高。张力的结果证明焊接关节的机械性质以静态的力量与贱金属的那些是可比较的并且根据在微观结构和焊接关节的机械性质之间的关系。焊接的最终的张力的强度等于时漏关节的，它显示横向的FZ的纵的FZ和那些的机械性质是一样。基础材料，关节，和焊接标本的Macromechanical行为和macrofracture和microfracture被观察。在标本破裂现象的三种类型之中的比较揭示下列特殊差别：(1)破裂模式，(2)在中央区域的酒窝模式的显微图，并且(3)在中央区域和转变区域的酒窝的尺寸。

简介：BackgroundTheeffectofselectiveradiofrequencyablationfortreatingparoxysmalsupraventriculartachycardia(PSVT)anditsassociatedparoxysmalatrialfibrillation(PAF)wasassessed.MethodsDatawerecollectedretrospectivelyfrompatientsdiagnosedofPSVTandsubsequentlytreatedwithradiofrequencyablation.Regularmonthlyfollow-upbydynamicelectrocardiography(ECG)wasperformed.Incidentratesofatrialfibrillationbeforeandafterablationwerecompared.Results382PSVTpatientswith58havingatrialfibrillationwereenrolled.TheorderofcomplicatedPAFfromhightolowinthesepatientswasdisplayedas:atrialtachycardia(AT),atrioventricularreentranttachycardia(AVRT)andatrioventricularnodalreentranttachycardia(AVNRT).AmongAVRTpatients,PAFwasmorefrequentinpatientshavingaccessorypathways.AVNRTpatientshadsignificantlylowerPAFratecomparingtootherpatients.PAFincidentratewassignificantlyreducedbyradiofrequencyablationtherapy.ConclusionWeadviseregulardynamicECGforPSVTpatients,especiallythosewithatrialflutter,ATorpre-excitationsyndrome.SelectiveradiofrequencyablationisafeasibleapproachfortreatingAFcomplicatedPSVTpatients.

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简介：Codfishisakindofabyssalfishspecieswithagreatvalueinfoodindustry.However,theflavorofcodfish,especiallytheunpleasantodor,hascausedseriousproblemsinitsprocessing.Toaccuratelyidentifythevolatilecompoundsincodfish,acombinationofsolidphasemicro-extraction(SPME)methodandsimultaneousdistillationextraction(SDE)methodwasusedtoextractthevolatiles.Gaschromatography-massspectrometry(GC-MS)alongwithKovatsindices(KI)andauthenticstandardcompoundswereusedtoidentifythevolatiles.Theresultsshowedthatatotalof86volatilecompoundswereidentifiedincodfish,ofthem24wereextractedbySDE,69compoundsbySPME,and10compoundsbybothSDEandSPME.Seventyvolatilecompoundswerefoundtohavespecificodors,ofthem7typicalcompoundscontributedsignificantlytotheflavorofcodfish.Alcohols(i.e.,(E)-2-penten-1-oland2-octanol),esters(i.e.,ethylbutyrateandmethylgeranate),aldehydes(i.e.,2-dodecenalandpentadecanal)contributedthemosttofreshflavorwhilenitrogencompounds,sulphurcompounds,furans,aswellassomeketones(i.e.,2-hydroxy-3-pentanone)broughtunpleasantodor,suchasfishyandearthyodor.ItwasindicatedthatthecombinationofmultipleextractionmethodsandGC-MSanalysiscanenhancetheaccuracyofidentification,andprovideareferenceforthefurtherstudyonflavorofaquaticproducts.

简介：Inthispaper,basedonGansuDigitalSeismicNetworkdatasince1990,wecalculatedb-valueand⊿b-valueoftheneighborhoodareabeforethe2013Minxian-ZhangxianM_S6.6,earthquake.Theresultsshowthattheearthquakeoccurredatthemarginofthesignificantlylowerb-valueareainsoutheastofGansuandbeforetheearthquaketheneighborhoodareahadanobviouslyabnormal⊿b-value.Fromtheearthquakeandthespatialdistributionoflowb-value,theregionstillhasthepossibilityofgeneratingdangerousstrongearthquakes.

简介：在中央台湾的Chenyulan溪流跟随是在台湾的一个主要边界差错的Chenyulan差错线。在最近的年里，许多破坏山崩在几强壮的台风伴随的重降雨以后发生在Chenyulan溪盆。在Chenyulan溪盆的山崩分布的三个例子，在1996前后并且在2004以后被分析。盒子尺寸和二点的关联尺寸被采用分别地描述在每二山崩之间的山崩区域尺寸分发和距离分发。山崩的数字在这个时期增加了，这被发现。然而，平均山崩区域减少了。关联尺寸逐渐地在这个时期期间从1.15～1.32增加了(在1996前后并且在2004以后)。这暗示在Chenyulan溪盆的山崩分发变得弥漫、广泛。框尺寸值显示出在一个空格占据的山崩密度的度。盒子尺寸也在这个时期期间从0.3～0.69增加了。山崩在这溪盆介绍了的增加的盒子尺寸工具逐渐地增加了。这显示这溪盆的斜坡变得更不稳定、易受影响。

简介：洋葱苍蝇，德莉娅antiqua，是能在夏天和冬季季节进入蛹的diapause的一个主要地下的农业害虫。然而，很少由于genomic资源的缺乏对它的分子的规定被知道。到进夏天diapause(SD)的可能的机制的获得卓见，高产量的RNA-Seq数据从non-diapause(ND)和SD被产生(起始，维护和静止阶段)蛹。三对明智的比较被执行并且识别，1380，1471和435，并且显著地被调整抄本。进一步的分析表明与少年荷尔蒙规定，房间周期，碳水合物和类脂化合物新陈代谢，天生的免疫者和应力有关的几个功能的学期的丰富回答，各种各样的发信号transductions，ubiquitin依赖的proteosome，并且变化在表皮并且细胞骨架部件在ND和SD之间并且在SD的不同阶段之间被发现。在SD和ND之间介绍的transcriptome的全球描述贡献SD的分子的机制的深入的说明。我们的结果也提供卓见进昆虫diapause的进化并且支持把洋葱苍蝇用作一个模型比较夏天和冬季diapauses的分子的规定事件的重要性。

简介：基于性交的bivariate频率分析能被用来在能被气候变化引起的Huai河盆在洪水特征调查变化。历史的洪水山峰，在19612000的最大的3天、7天的卷和在20612100的未来值的univariate分布在A2，A1B和B1下面从二投射了GCM(CSIRO-MK3.5和CCCma-CGCM3.1)排放情形被分析并且比较。然后，山峰和体积的bivariate分布基于性交方法被构造，在联合回来时期的可能的变化被描绘。结果显示Clayton性交是更适当的为历史并且CCCma-CGCM3.1模仿洪水变量，当弗兰克和Gumbel的更好被适合到CSIRO-MK3.5模拟时。univariate和bivariate回来时期的变化表明洪水特征可能比不同排放情形对不同GCM更敏感。在二GCM之间，CSIRO-MK3.5显然在未来预言更严重的洪水条件，特别在B1情形下面，而CCCma-CGCM3.1通常建议矛盾的变化信号。这研究支持性交能用作一个可行、灵活的工具连接univariate边缘的分布充满变量并且确定联系了风险，它可以为基于风险的洪水控制提供有用信息。

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简介：Tosystematicallystudythevehicle–bridgecoupleddynamicresponseanditschangerulewithdifferentparameters,avehiclemodelwithsevendegreesoffreedomwasbuiltandthetotalpotentialenergyofvehiclespacevibrationsystemwasdeduced.Consideringthestimulationofroadroughness,thedynamicresponseequationofvehicle–bridgecoupledsystemwasestablishedinaccordancewiththeelasticsystemprincipleoftotalpotentialenergywithstationaryvalueandthe‘‘set-in-right-position''rule.Onthebasisoftheself-compiledFortranprogramandbridgeengineering,thedynamicresponseoflongspancontinuousgirderbridgeundervehicleloadwasstudied.Thisstudyalsoincludedthecalculationofvehicleimpactcoefficient,evaluationofvibrationcomfort,andanalysisofdynamicresponseparameters.Resultsshowtheimpactcoefficientchangeswithlanenumberandislargerthanthevaluecalculatedbythe‘‘generalcodefordesignofhighwaybridgesandculverts(China)''.TheDieckmannindexofbridgevibrationisalsorelatedtolanenumber,andthevibrationcomfortevaluationisgoodinnormalconditions.Therelevantconclusionsfromparametricanalyseshavepracticalsignificancetodynamicdesignanddailyoperationoflong-spancontinuousgirderbridgesinexpressways.Safetyandcomfortareexpectedtoimprovesignificantlywithfurthercontrolofthevibrationofvehicle–bridgesystem.