简介:河流相砂体横向相变快,连续性和连通性差,储层非均质性强.严重影响了河流相储层的开发效果。依据储层沉积学的研究方法,对苏里格气田苏14井区盒8段河流相砂体展布与演化规律进行了研究。结果表明:苏14井区盒8段属于早期辫状河沉积向晚期曲流河沉积逐渐转化的沉积背景,其主要沉积微相包括河道滞留沉积、心滩、边滩、决口扇、天然堤、河漫砂及泛滥泥。受基准面升降与沉积物供应的共同作用,该区河流相砂体演化呈阶段性变化,大致经历了辫状河繁盛发育期、辫一曲共存转化发育期及曲流河繁盛发育期3个阶段,其中辫状河繁盛发育期的心滩砂体与辫一曲共存转化发育期的心滩及边滩砂体是主力含气储层。研究区优质储集砂体的发育受沉积微相展布与基准面旋回的控制。
简介:摘要:东胜气田J58井区具有低饱和度高液气比特点,产量递减快,部分气井地层出水严重、井底积液影响气井正常生产。本文通过分析1口深度超过2800m水淹气井地质条件、井身结构,制定机抽排水采气工艺措施,完善配套工艺设备,开展现场试验,探索水淹关井气井机抽排采复产工艺。
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简介:AbstractObjective:The asparagine-linked glycosylation 13 homolog (Alg13) has been identified as causative for congenital disorders of glycosylation type I with epilepsy. The aim of this study was to determine whether mice carrying a mutated version of Alg13 could be used as a model for epileptic encephalopathies or congenital disorders of glycosylation type I.Methods:A model of epileptic encephalopathy was established in C57BL/6 mice by introducing mutations in Alg13 via the clustered regularly interspaced palindromic repeats (CRISPR)/CRISPR-associated protein 9 (CRISPR/Cas9) system. All surgical procedures were approved by the Institutional Animal Care and Use Committee of Shanghai Jiao Tong University (A2016084) on October 8, 2016.Results:Mice with 3 different mutations, Alg13-54nt, Alg13-5nt and Alg13-4nt, all of which are located in Alg13 transcript variant 1, were created. The Alg13-5nt mice exhibited spontaneous seizures similar to patients with Alg13 mutations, suggesting that they could be used as a model for epilepsy. Western blot analysis demonstrated that Alg13-5nt mice had lower levels of Alg13 expression than wild-type mice. Video observations showed that two of the 17 Alg13-5nt mice had stage 5 seizures involving jumping and falling, while 12 had stage 3 seizures with head nodding.Conclusion:The Alg13 mouse model provides an outstanding tool for studying epileptic encephalopathies and investigating different aspects of defects in glycosylation or other post-translational modification that cannot be assessed in patients or cell culture systems.
简介:摘要:通过国内外调研,本文分别从国内外几大页岩气区块进行深度剖析。重点阐述了国外Haynesville、EagleFord、CanaWoodford、Hilliard-Baxter-Mancos和Mancos等5个深层页岩气区块的分布特点及开发进程。至于国内页岩气从大陆地质构造阐述深层页岩气地质分布特点,以及南北方区域的划分,明确了国内深层页岩气分布的沉积环境。
简介:摘要:以气田轻烃生产为例,实际运行中会产生重色轻烃,重色轻烃在交接运营中会发生因色差,产生降密问题,造成了经济损失及对后持续生产运营造成了一定影响,经过前期实验,使用适当具有表面吸附性可将轻烃中的有色成分吸附达到脱色的目的,且对轻烃PH值、辛烷值等无影响,骨炭是最早应用于工业制糖脱色使用,但因其存在一定缺陷逐渐被活性炭取代,活性炭有颗粒和粉末两种,本次实验为粉末活性炭,粉末活性炭表面积大,吸附能力较强,本文对气田产出轻烃进行脱色实验,并讨论活性炭的若干问题。