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简介：Theearlydiagnosisofcardiacruptureisoneofthekeyfactorsforasuccessfuloutcome.However,theaccuratediagnosisisoftendifficultintheearlystageofinjury,especiallywhensomeobviousseverewoundsarefoundinotherregionsofthebody,1,2fortheyareeasytodisguisethesymptomoftheheart.Wereportacasewithcardiacruptureandlivertraumacausedbytrafficaccident.

简介：Objective:Toinvestigatetheeffectof360-degreeretinectomyforsevereocularruptureandevaluatetherelatedfactorsassociatedwithprognosis.Methods:Aretrospectiveanalysiswasperformedon28consecutivepatients,18menand10women,withsevereocularruptureadmittedtotheChinesePLAGeneralHospitalbetweenJanuary1999andJanuary2002.Thepatients'agesrangedfrom16to58years,mean29.5years.Alloperationswereperformedbythefirstauthor.Allpatientsunderwentstandard3-portparsplanavitrectomywithscleralencirclingbuckle,endophotocoagulation,andtamponadedwithsiliconeoil.Lensectomywereperformedon15eyes.360-degreeretinotomyandretinectomywereperformedatanteriorequatoron16eyes,andposteriorequatoron12eyes.Results:Duringoperation,allpatientswereconfirmedtohavevitreoushemorrhageandretinaldetachment,inwhichhemorrhagicciliarybodydetachmentwasfoundin9eyes,suprachoroidalhemorrhagein12eyes,retinaltwistinglikeflowerstalkin11eyes,andretinalincarcerationin17eyes.Postoperativefollow-upwasconductedin26cases,rangedfrom6monthsto46months.Retinalreattachmentachievedin20eyes(76.9%),inwhichthreepatients'retinawasreattachedafterrevitrectomy.Thesiliconeoilwasremovedatthefourthmonthin8eyespostoperatively.Correctedvisualacuityof0.02ormorewasin14eyes(70.0%)amongthe20patientswithreattachedretina.Visualacuityof0.05ormorewasin7eyes(35.0%),and0.1ormorewasin3eyes.Thebestvisualacuitywas0.3in1eye.Conclusions:Retinectomymayimprovetheprognosisofsevereocularruptureandsavethevisualfunctionofsomepatients.

简介：ＡｎａｌｙｓｉｓｏｎｒｕｐｔｕｒｅｆｅａｔｕｒｅｏｆａｇｒｅａｔｃｏｍｐｌｉｃａｔｅｄｅａｒｔｈｑｕａｋｅｉｎＫａｍｃｈａｔｋａＹＵＡＮＧＡＯ１）（高原）ＳＩＨＵＡＺＨＥＮＧ１）（郑斯华）ＨＵＩＬＡＮＺＨＯＵ２）（周蕙兰）ＺＨＥＮＬＩＵ２）（...

简介：Theunpredictableruptureofsaccularaneurysmsespeciallyoftheintracerebralaneurysmisaknottyproblemthatalwaysresultsinhighmortality.Traditionaldiagnosisofmedicalimages,whichgivestheaneurysmsizeandcompareswithaspeculatedcriticalsizefromclinicalstatistics,wasdemonstratedinadequatetoforecastingrupture.Here,weproposeanewdetectingstrategythatusesadielectricelastomer(DE)capacitancesensortomonitorthegrowthofsaccularaneurysmsanddeliverboththewallstressandgeometricparameters.Basedontheelasticgrowththeorytogetherwiththefinitedeformationanalyses,thecorrelationbetweenthereal-timeoutputcapacitanceoftheDEsensorandthewallstressand/orgeometryofananeurysmisderived.Comparedtoclinicstatisticsandbiomechanicssimulations,thewallstressandgeometricsizemaybeusedascombinedindicatorstoassesstheruptureriskofasaccularaneurysm.Numericalresultsshowthatanoutputrelativecapacitanceof30indicatesahighriskofrupture.Finally,thesensitivityandresolutionoftheDEsensorareprovedadequatelyhighformonitoringthegrowthstateandevaluatingtheruptureriskofasaccularaneurysm.

简介：Theexperimentalstudywasperformedin78rabbits,theexposedanteriorven-tricularsurfaceoftheopen—chestrabbitswereimpactedwithapendulum—likemovementimpactorsystemwhichwascontrolledbytheCardiaccycle.Undrsomegivenconditions,theexperimentalresultswereasfollows:（1）Theimpactsat5.0m·s-1resultedinnocardiacruptureinallattemps（16/16）attheendofsystoleas

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简介：AbstractThis study reported a case of spontaneous rupture of an ovarian artery aneurysm 4 days following cesarean section. The patient mainly presented with a consistent low-grade fever and did not have symptoms, such as severe abdominal or flank pain, as is common in other similar cases. Enhanced magnetic resonance imaging revealed a massive retroperitoneal hematoma; angiography confirmed that there was a rupture in an ovarian artery aneurysm. A selective embolization was performed successfully.

简介：Toreproducetheprematureruptureprocessofmetalsheetsubjectedtolaserirradiationwithsubsonicairflow,whichisaninterestingphenomenonobservedintheexperimentsgivenbyLawrenceLivermoreNationalLaboratory,acouplednumericalmodelconsideringtheinteractionandevolutionofmetalelastoplasticdeformationandaerodynamicpressureprofileispresented.Withthethermalelastoplasticconstitutiverelationshipandfailurecriterion,thesimulatedfailuremodesanddynamicruptureprocessarebasicallyconsistentwiththeexperimentalresults,indicatingplasticflowandmultiplefracturingisthemainfailuremechanism.Comparedwiththecaseofnon-airflow,subsonicairflownotonlyacceleratesdeformation,butalsoturnsthebugledeformation,plasticstrainandrupturemodeintoasymmetric.

简介：ＴＤｅｐａｒｔｍｅｎｔｏｆＣｌｉｎｉｃａｌＲａｄｉｏｌｏｇｙ，ＦｉｒｓｔＨｏｓｐｉｔａｌ，ＢｅｉｊｉｎｇＭｅｄｉｃａｌＵｎｉｖｅｒｓｉｔｙ，８ＸｉｓｈｉｋｕＳｔｒｅｅｔＢｅｉｊｉｎｇ１０００３４，Ｃｈｉｎａ（ＷａｎｇＲＧ，ＧａｏＹＪａｎｄＬｉＳＮ）Ｄ...

简介：AbstractBackground:Deregulation of miRNA-21 expression has been reported to be associated with vascular smooth muscle behavior and cytoskeletal stability. This study is aimed to investigate the density of serum miRNA-21 in patients with different phases of intracranial aneurysms (IAs) and explore its warning function for IA rupture.Methods:A total of 16 in 200 IA patients were selected and categorized into 4 groups based on the phase of IA. Microarray study was carried out using serum miRNA and differentially expressed miRNAs were identified. Another 24 samples from a cohort of 360 patients were added and real-time polymerase chain reaction (RT-PCR) was performed on expanded sample size (n = 40) for miRNA-21 validation. Potential gene targets of miRNA-21 were screened out from Gene Ontology (GO) database and literatures.Results:Microarray study identified 77 miRNAs with significantly different expression levels between experimental groups and the control group. RT-PCR assays validated significant downregulation of miRNA-21 in experimental groups, among which miRNA-21 expression level of daughter aneurysm group decreased the most. Bioinformatic analyses revealed that several target genes related with miRNA-21 may be involved in IA formation and rupture.Conclusions:This study suggested that miRNA-21 had a protective effect for intracranial vascular wall against remodeling and warning function for intracranial aneurysm rupture. Significant suppression of serum miRNA-21 in IA patients may provide diagnostic clues for aneurysm rupture and guide clinical intervention.

简介：使用的地面运动的择向性上的地震超级砍破裂的效果模仿了一个垂直罢工滑倒差错模型的加速是这研究的话题。分离波浪number/finite元素方法被采用在水平分层的一半计算扎根的运动空间。山峰地面加速(针网阵列)的分析显示那类似于亚shear状况，择向性也处于超级砍状况存在。然而，如下有一些差别：(1)差错正常部件的针网阵列与被择向性显著地在处于一种超级砍状况处于一种亚shear状况在前面的方向从一个锥形的区域改变到一个有限近差错的区域的PGA地里影响的超级砍速度，和区域减少。(2)差错平行和垂直部件的针网阵列不象到增加的超级砍速度的差错正常部件一样敏感。(3)当破裂速度超过shear波浪速度时，差错正常部件的针网阵列不总是比差错平行部件大。

简介：A3-Dsoil-pipenonlinearfiniteelementmodelwithcontactelementissuggestedandtheinfluencesoftherupturemode,thicknessandrigidityofoverlyingsoilontheresponseofburiedpipelineareanalyzed.Thenumericalresultsshowthatthesoilrupturemodedeterminesthelocationofthelargedeformationorfailureofthepipeline,andtheplasticdeformationofthepipelineoccursatthezonewheretheplasticdeformationorruptureoftheoverlyingsoilappears.Whenthefaultdipangleonbedrockisnear90°,twoplasticdeformationsectionsofthepipelineappearwiththedevelopmentofoverlyingsoilrupture.Andthethickertheoverlyingsoilis,thelongertheplasticdeformationlengthofthepipelineisandthelessitsstrainis.Theplasticdeformationlengthofthepipelinedecreaseswhileitsmaximumstrainincreaseswiththerigidityofoverlyingsoilincreasing.

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简介：High-frequencyruptureprocessoftheOct23,2011Van-Merkezearthquakeisimagedbyback-projectionmethodusinghigh-qualityteleseismicPwavedatafromtheUSArray,andprestackKirchhoffmigrationusingPwavedatafromasubarrayofglobalseismicnetworks.Therupturemodelwithtwoasperitiesisconfirmedbyprevioustwomethods.Inlow-frequencyimaging,alargeasperityderivedfromthemigrationmethodcorrespondstothesecondonefromthehigh-frequencyPwaves.Theconsistencyofthelocationsofasperitiesfromdatasetswithdifferentfrequencybandsindicatesthatthereispossibleinsignificanceofthefrequency-dependentfeaturefortheearthquake.Theresultantimagesillustratethespatialandtemporalevolutionoftherupture,whichmainlypropagatedWSWoveralengthof33kmduringthefirst18s,accompanyingwithburstsoftwoasperitiesat3and11–13s.TherupturedirectionisconfirmedbytheSwavecornerfrequencyvariationsofstronggroundaccelerations.Therupturefrontsaremainlylocatedattheupdipofthecausativefault.BasedonpolaritiesofthePwaveformsandfocalmechanismsofthemainshockandaftershocks,thefailureofthesetwoasperitiesisdeterminedtohaveoccurredonareversefaultwithadipangleof47°.Hence,therupturepatternofthe2011Van-Merkezearthquakewasdominatedbyaunilateralrupturetowardthewestsouthwestdirection.

简介：The13November2016KaikouraearthquakeoccurredinthenortheasterncoastalregionoftheSouthIsland,NewZealand.TheMw7.8mainshockgeneratedacomplexpatternofsurfaceruptures,andwasfollowedwithinabout12hoursbythreemoderateshocksofMw≥6.0.HereweuseteleseismicwaveformstoinvertforthesourceruptureoftheKaikouraearthquake.Theresultingslip-distributionmodelexhibitsinsignificantslipnearthehypocenterandthreepocketsofmajorslipzoneswithdistinctsensesofmotion.Themainshockstartedfromarupturenearthehypocenter,grewintothrustonshallowcrustalfaults~50kmnortheastofthehypocenter,andthendevelopedintotwoslipzones:adeeperonewithobliquethrustandashalloweronewithalmostpurelyright-lateralstrike-slip.Locationsofthethrustandstrike-slipmotionsintheslip-distributionmodelagreewellwithreportedcoastalupliftsandhorizontaloffsets.Theoverallslippatternisdominatedbyhorizontalmotion,especiallyatshallowdepth,duetothepartitioningofthrustandstrike-slipmotionsabovethesubductionzonemegathrust.Aftershockdistributionsuggeststhatmostaftershockstendtooccurneartheedgesofthemajorslipzonesofthemainshock.Thisobservationonaftershocklocationsmayprovideusefulinformationforseismichazardassessmentsafterlargeearthquakes.

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简介：AbstractBackground:Preterm premature rupture of membranes (PPROM) is associated with high neonatal morbidity and mortality. However, the influences of cesarean section (CS) on neonatal outcomes in preterm pregnancies complicated with PPROM are not well elucidated. The aim of this study was to investigate the influence of delivery modes on neonatal outcomes among pregnant women with PPROM.Methods:A retrospective cross-sectional study was conducted in 39 public hospitals in 14 cities in the mainland of China from January 1st, 2011 to December 31st, 2011. A total of 2756 singleton pregnancies complicated with PPROM were included. Adverse neonatal outcomes including early neonatal death, birth asphyxia, respiratory distress syndrome (RDS), pneumonia, infection, birth trauma, and 5-min/10-min Apgar scores were obtained from the hospital records. Binary variables and ordinal variables were respectively calculated by binary logistic regressions and ordinal regression. Numerical variables were compared by multiple linear regressions.Results:In total, 2756 newborns were involved in the analysis. Among them, 1166 newborns (42.31%) were delivered by CS and 1590 newborns belonged to vaginal delivery (VD) group. The CS proportion of PPROM obviously increased with the increase of gestational age (χ2 = 5.014, P = 0.025). Compared with CS group, VD was associated with a higher risk of total newborns mortality(odds ratio [OR], 2.38; 95% confidence interval [CI], 1.102–5.118; P = 0.027), and a lower level of pneumonia (OR, 0.32; 95% CI, 0.126–0.811; P = 0.016). However, after multivariable adjustment and stratification for gestational age, only pneumonia was significantly related with CS in 28 to 34 weeks group (OR, 0.34; 95% CI, 0.120–0.940; P = 0.038). There were no differences regarding to other adverse outcomes in the two groups, including neonatal mortality, birth asphyxia, Apgar scores, RDS, pneumonia, and sepsis.Conclusions:The proportion of CS of pregnant women with PPROM was very high in China. The mode of delivery does not affect neonatal outcomes of pregnancies complicated with PPROM.

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