简介:Capacitydepletionisanimportantinformationrequiredforplanningofmultipurposereservoirs.Itisacomplexphenomenoninvolvingdiversefieldslikesurfacehydrology,sedimenttransport,variedflowhydraulicsandsoilconsolidation.Properassessmentofcapacityreductionishelpfulinascertainingthelifeofthereservoirandtheprojectbenefitsforcost/benefitanalysis.Inthisstudydimensionallyconsistentequationsfordepositionvolumeandthetrapefficiencyhavebeenobtained.Methodsofobtainingtheparametersinvolvedtheseequationshavealsobeenindicated.Itwasfoundthatthereisgoodagreementwiththefielddata.Itishopedthattheequationsareusefultodesignengineer.
简介:Therearefewpapersintheliteraturefocusingontheissueoftheoptimaldepletionofexhaustibleresourcesintheframeworkofvariabletimepreference.Thispaperattemptstoanalyzethepureconsumptionofexhaustibleresourceunderhyperbolictimepreference,andtodiscusstheoptimaldepletionrateandtheeffectoftheprotectionoftheexhaustibleresourceunderdifferentcommitmentabilities.Theresultsofmodelshowthatthecaseofthehyperbolicdiscountwiththefullcommitmentofthegovernmentisequivalenttothecaseofconstantdiscountofthesocialplannerproblem.Inthatcase,theoptimaldepletionrateandtheinitialconsumptionofexhaustibleresourcearetheslowest.Onthecontrary,theyarethehighestandthemyopicbehaviorsleadtoexcessiveconsumptionofexhaustibleresourcesinevitablywithoutcommitment.Otherwise,inthecaseofpartialcommitment,theresultsarebetweenthecasesoffullcommitmentandofnocommitment.Therefore,withthehyperbolictimepreference,theoptimaldepletionrateofresourcedependsonthecommitmentability.Highercommitmentabilityleadstolowereffectiverateoftimepreference,andconsequently,lowerdepletionrateandlowerinitialdepletionvalue.Theimprovementofcommitmentabilitycandecreasetheimpatienceandmyopiabehaviors,andcontributetotheprotectionoftheexhaustibleresources.
简介:TherearenotabledifferencesintheincidenceandmortalityratesforprostatecancerbetweenAsiaandWesterncountries.Itisalsorecognizedthattherearedifferencesinthinkingwithregardtotreatmentoptions.RecentlyitisalsothecasethatopinionshavebeenreportedconcerningthedifferencesbetweenAsianandWesternpatientswithregardtotheirreactiontoandrogendepletiontherapy(ADT).GiventhatADTisamethodoftreatmentthatfocusesontheeliminationoftestosterone,aninevitablesymptomofitsadministrationistestosteronelosingsyndrome.ItisforthisreasonthatinWesterncountriesADThasonlybeenrecommendedincasesofadvancedormetastaticcancer.Ontheotherhand,inAsia,ADTisusedinrelativelymanycases,includingnon-metastaticlocalizedcancerandinvasivelocalizedcancer.Todate,however,therehasbeenlittlesubstantivediscussionconcerningthisdifferenceinutilizationofADT.ADT-relateddrugsforprostatecancerandthedevelopmentofnewdrugsforcastrationresistantprostatecancer(CRPC)havebeenactivelytestedinrecentyears.ItcouldbethecasethatanalyzingthedifferencesinconceptsaboutADTbetweenAsiaandtheWestcouldcontributetotheeffectiveuseofADT-relateddrugsandalsohelptobuildnewtreatmentstrategiesforprostatecancer.
简介:DepletionmodeHEMTwithrefractorymetalsilicideWSigatehasbeende-signedandfabricated.Epicated.Epitaxialmodulationdopingmaterialsweregrownbyahome-madeMBEsystem.Thegatelengthandwidthforlownoisedepletiondeviceswere1.2~1.5μmand2×160μmrespectively.Theelectronmobilityofthefabricateddevicesistypically6080cm^2/V·sat300Kand68000cm^2/V·sat77K.Thesheetelectronconcentrationnsis9×10^11cm^-2,Thesource-draincontactswithAuGeNi/Auwerefabricatedusingevaporatingandlift-offtechnique.tofurtherreducethecontactresistance,thewaferalloyedat520℃for3mininthehydrogen(H2)gas.SchottkygatewasformedusingWSi.Thetranseon-ductanceofthedepletionmodedeviceis110~130mS/mmatroomtemperature,Thede-vicescanbeappliedincommunicationsatelliteatmicrowavefreqencyof3.83GHzandradarreceiverat1.5GHz.Itsnoisefigureisabout2~3dB.
简介:AerosolsampleswerecollectedonboardtheresearchvesselXuelongduringtheFifteenthChineseAntarcticResearchExpedition(CHINAREXV)inNovember1998-April1999andtheFirstChineseArcticResearchExpeditioninJuly-September1999.TheareastraversedbytheexpeditionarycruisesincludetheArcticOcean,thewesternNorthPacificOceanandtheeasternIndianOcean,covering75°N-69°Sand75°E-133°W.AerosolsampleswerealsotakenattheChineseZhongshanStationinEastAntarcticaduringtheCHINAREXV.Analysisofthesamplesyieldedconcentrationsofnon-sea-saltsulfateandothersolublechemicalspeciesinthemarineboundarylayer.Thedatasuggestthatthechemicalcompositionofthemarineaerosolsisinfluencedbythreemajorsources:continentalairmasses,primaryoceanicemissions,andsecondarymarineaerosolsoriginatedfromoceanicemissions.Theresultsshowthat,awingtostronganthropogenicsulfuremissionsfromtheAsiancontinent,non-sea-saltsulfateconcentrationsintheNorthernHemisphere(thewesternNorthPacific)marineaerosolaresignificantlyhigherthanthoseintheSouthernHemisphere(theeasternIndianOcean).Aerosolnon-sea-saltsulfateconcentrationsappeartobeinverselycorrelatedwithaerosolnon-sea-saltchloridewhichshowssignificantlynegativevalues,indicatingthelossofchloridebyseasalts,inmostaerosolsamples.SincegaseousHClmaybeinvolvedinchemicalreactionsthatdepleteatmosphericozoneinthemarineboundarylayer(MBL),highlevelsofacidicnon-sea-salt-sulfatereleasedbyhumanactivitiesinthelowandmid-latitudesoftheNorthernHemispheremaybecomeanimportantpotentialcontributortothelossofatmosphericozoneintheMBL.
简介:Anovelstructureisproposedfordoublingtheverticalbreakdownvoltageofsilicon-on-insulator(SOI)devices.Inthisnewstructure,theconventionalburiedoxide(BOX)inanSOIdeviceissplitintotwosections:thesource-sectionBOXandthedrain-sectionBOX.Ahighly-dopedSilayer,referredtoasanon-depletionpotential-clampedlayer(NPCL),ispositionedunderandclosetothetwoBOXsections.InthesplitBOXesandtheSiregionabovetheBOXes,theblockingvoltage(BV)isdividedintotwopartsbytheNPCL.ThevoltageintheNPCLisclampedtobenearlyhalfofthedrainvoltage.Whenthedrainvoltageapproachesabreakdownvalue,thevoltagesustainedbythesource-sectionBOXandtheSiregionunderthesourcearenearlythesameasthevoltagesustainedbythedrain-sectionBOXandtheSiregionunderthedrain.TheverticalBVisthereforealmostdoubled.TheeffectivenessofthisnewstructurewasverifiedforaP-channelSOIlateraldouble-diffusedmetal-oxidesemiconductor(LDMOS)andcanbeappliedtootherhigh-voltageSOIdevices.ThesimulationresultsshowthattheBVinanNPCLP-channelSOILDMOSisimprovedby55%andthespecificon-resistance(Ron,sp)isreducedby69%incomparisontotheconventionalstructure.
简介:Magneticspectrumoftheelectromagneticioncyclotronwavesintheterrestrialplasmadepletionlayer(PDL)aresometimesobservedtohaveaBIF(bifurcated)signature,whereadiminutionaround0.5ΩpwithΩptheprotongyrofrequency,occursbetweentwoactivitypeaksinthespectrum.Byone-dimensionalhybridsimulations,theeffectofrelativedriftvelocitiesbetweenprotonsandHe2+onthemagneticspectralsignaturesinthePDLisstudied.Theresultsshowthattherelativedriftvelocityenhancesthedevelopmentofprotoncyclotronwavesanddeclinesthedevelopmentofheliumcyclotronwaves.Theprotoncyclotronwavesarefirstlyexcited,andfollowedbytheexcitationofheliumcyclotronwavesduetotheincreaseintherelativedriftvelocity.Moreover,theboundarybetweentwoactivitypeaksgetsobscure.
简介:AIMTo学习discoidin象我一样domaincontaining蛋白质3的效果(EDIL3)在人的透镜的增长和上皮间充质的转变(EMT)上的弄空上皮的房间(LEC).METHODSRNA干扰被用来在vitro在人的LEC禁止EDIL3的表示。房间的形态学用一台转换显微镜被观察。房间增长用EdU工具包被估计。房间移植用Transwell房间被调查,LEC的EMT用共焦的显微镜并且西方的弄污被估计。转变生长因素(TGF)小径用数据显示出的西方的blotting.RESULTSThe被调查那个silencingEDIL3表达式改变了LEC形态学并且压制了LEC增长(P<0.05)并且移植(P<0.01)。而且,西方的弄污的结果证明那EDIL3弄空减少了光滑的肌肉肌动朊的表示(-SMA)(P<0.001)并且vimentin(P<0.01),当增加时E-cadherin的表示(P<0.001)。EDIL3弄空能压制Smad2的phosphorylation(P<0.01)并且Smad3(P<0.01)并且exracellular信号的激活调整了kinase(英皇家空军之阶级最低之兵)(P<0.05).CONCLUSIONThe调查结果显示EDIL3可能经由TGF小径在LEC参予增长和EMT并且可以是为以后的囊opacification的处理的一个潜在的治疗学的目标。
简介:Reductionofmodulatorenergyconsumptionto10fJ∕bitisessentialforthesustainabledevelopmentofcommunicationsystems.Lumpedmodulatorsmightbeaviablesolutionifinstructedbyacompletetheorysystem.Here,wepresentacompleteanalyticalelectro-opticresponsetheory,energyconsumptionanalysis,andeyediagramsonabsolutescalesforlumpedmodulators.Consequentlythespeedlimitationisunderstoodandalleviatedbysingle-driveconfiguration,andcomprehensiveknowledgeintotheenergydependenceonstructuralparameterssignificantlyreducesenergyconsumption.Theresultsshowthatsiliconmodulationenergyaslowas80.8and21.5fJ∕bitcanbeachievedat28Gbdunder50and10Ωimpedancedrivers,respectively.A50Gbdmodulationisalsoshowntobepossible.Theanalyticalmodelscanbeextendedtolumpedmodulatorsonothermaterialplatformsandofferapromisingsolutiontothecurrentchallengesofmodulationenergyreduction.
简介:Aone-dimensionaltime-dependentphotochemicalmodelisusedtosimulatetheinfluenceofion-producedNOxandHOxradicalsontheAntarcticozonedepletioninpolarnightandpolarspringatalatitudeof73degreessouth.Verticaltransportandnitrogen-oxygen(NOx).hydrogen-oxygen(HOx)productionbyionicreactionshavebeenintroducedintothemodel.NOxandHOxproducedbyprecipitatingionsaretransportedintothelowerstratospherebyverticalmotionandhavesomeeffectsinthedevelopmentoftheAntarcticozonedepletion.Fromwinterthroughspringthecalculatedozonecolumndecreasesto269.4DU.However,thisvalueissignificantlyhigherthanthetotalozoneobservedatseveralAntarcticozonestations.