简介：<正>DuringthefourandhalfmonthsofmystayingattheAlbrightInstituteofArchaeologicalResearchinJerusalemandintheHebrewUniversity(01.12.2013–13.04.2014),Ihadthechancetoreadandstudysomeunpublishedcuneiformtablets.Here,IwouldliketomakeasmallcontributiontotheworkofpublishingthepreciousinformationhiddeninthecuneiformtabletsfromancientMesopotamia,andhopethatsomecolleaguescangivesomeimprovedreadingto

简介：CuneiformtextspresentedinthisarticlearepartoftheAvcollectionofcuneiformtabletsbelongingtoaprivatecollectorinJerusalem.Iwasintroducedtothiscollectionalmostacoupleofyearsagobyachancethroughamutualfriend.Thecollectionwas

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简介：基于有安培计的察觉(CZE广告)的毛状的地区电气泳动，一个简单、可靠、可再现的方法包括paracetamol，维生素C，咖啡的酸和chlorogenic酸在VcYinqiao药片为四活跃成分的同时的决心被开发了。一个碳磁盘电极被用作工作电极和0.95V(对SCE)作为察觉潜力被选择。CZE实验的最佳的条件是30mmol??Д

简介：健康志愿者１０名，随机交叉口服硫酸吗啡控释片（ＣＲＭＳ）３０ｍｇ（３０ｍｇ×１）和硫酸吗啡普通片（ＩＲＭＳ）２０ｍｇ（１０ｍｇ×２），分别于服药前后各时点取静脉血，用ＧＣＭＳ测定血浆中吗啡含量。以药代软件程序处理，分别求得ＣＲＭＳ和ＩＲＭＳ的Ｃｍａｘ为１９．３８±３．８０和２１．２７±６．２１ｎｇ／ｍｌ；ｔｍａｘ为２．３６±０．３７ｈ和０．５５±０．１６ｈ；ｔ１／２β为３．５３±０．８７ｈ和３．０３±０．７４ｈ，曲线下面积ＡＵＣ为１４５．１５±１７．６５和９３．０８±１６．６５ｎｇ·ｈ／ｍｌ。癌症病人多次口服硫酸吗啡至稳态，ＣＲＭＳ和ＩＲＭＳ的峰浓度分别为２７．４３±０．３３ｎｇ／ｍｌ，２２．６８±０．１６ｎｇ／ｍｌ；谷浓度分别为１９．４５±１．４４ｎｇ／ｍｌ；１８．１４±０．４９ｎｇ／ｍｌ。

简介：Inthepresentstudy,weaimedtodeterminethequalityofdifferentbrands(Test1–Test6)ofmefenamicacid,whicharecommerciallyavailableinlocalmarketofKarachi,Pakistan.Variousqualityevaluationtests,includingweightvariation,hardness,thickness,friability,disintegration,assayanddrugrelease,werecarriedout.Resultswerefoundtobeinacceptablelimits.Moreover,releaseprofileswerecomparedusingdifferentdissolutionmedia,suchasphosphatebufferpH6.8,7.4andbiorelevantmedia(FaSSGF,FaSSIF,FeSSIFandSCoF).ReleaseprofilesatpH6.8and7.4wereevaluatedbyone--wayANOVA,model-independentandmodel--dependentmethods.ResultsofANOVAshowedthatnosignificantdifferencewasfoundamongtesterandreferencebrands(Test1–Test6).Similarly,allthebrandswerefoundtobebestfittedwithWeibullmodel.

简介：Thepresentstudywasdesignedtoestablishamulti-wavelengthquantitativefingerprintingmethodforSan-HuangTablets(SHT),awidelyusedandcommerciallyavailableherbalpreparation,wherehighperformanceliquidchromatography(HPLC)withadiodearraydetector(DAD)wasemployedtoobtainthefingerprintprofiles.Asimplelinearquantitativefingerprintmethod(SLQFM)coupledwithmulti-ingredientsimultaneousdeterminationwasdevelopedtoevaluatethequalityconsistencyofthetestedsamplesqualitativelyandquantitatively.Additionally,thecomponent–activityrelationshipbetweenchromatographicfingerprintsandtotalradical-scavengingcapacityinvitro(asassessedusingthe1,1-diphenyl-2-picrylhydrazyl(DPPH)assay)wasinvestigatedbypartialleastsquaresregression(PLSR)analysistopredicttheantioxidantcapacityofnewsamplesfromthechromatographicfingerprintsandidentifythemainactiveconstituentsthatcanbeusedasthetargetmarkersforthequalitycontrolofSHT.Inconclusion,thestrategydevelopedinthepresentstudywaseffectiveandreliable,whichcanbeemployedforholisticevaluationandaccuratediscriminationforthequalityconsistencyofSHTpreparationsandothertraditionalChinesemedicine(TCM)andherbalpreparationsaswell.