简介:自己组装在自然占优势并且从自然学习将导致biofunctional材料。由弹力素的蛋白质启发了,我们在忍受重复VPGAG的肽的弹力素的超分子的hydrogel上在这研究报导了。粘弹性性质,nanostructures的形态学,并且在自我装配的nanostructure的芳香的叠被电流测定,传播电子显微镜(TEM),和荧光显微镜分别地描绘。gelator的biocompatibility被MTT试金也证明。尽管超分子的hydrogel没能展出象弹力素一样的高弹性,thixotropichydrogel可能在房间文化的领域里为应用有潜力,控制药版本,等等。
简介:(丙烯酸的酸)Chitosan-poly,hydrogel与Eu3+结合了被激进的溶液聚合准备。可被细菌破坏的chitosan,N,N-methylen-diacrylamide,和钾过硫酸盐分别地被用作基本材料,cross-linking代理人,和开始者。结构和hydrogel的热性质被红外线的spectrometry,X光检查衍射,扫描电子显微镜学,和微分扫描热量测定描绘。肿的性质并且荧光灯性能也被描绘。结果证明稀土元素在聚合以后由于化学契约的形成在hydrogel介绍了唯一的分发。hydrogel的玻璃转变温度显著地减少了,它可能更加拓宽它的有弹性的申请的范围。而且,特征荧光灯Eu3+的排放在hydrogel被观察,它优秀光表演是指示的。
简介:为软织物重建得到一种新支架材料,我们通过混合crosslinked准备了XLHA-PNIPAAm和XLHA-MC血管注射剂hydrogels哈(XLHA)并且二温度敏感的材料poly在降级不同(N-isopropylacrylamide)(PNIPAAm)并且methylcellulose(MC)分别地。我们测试了injectablility,酶的biodegradability,温度敏感,结构cytotoxicity和二血管注射剂hydrogels的溶血。我们的研究成功地获得了XLHA-PNIPAAm血管注射剂hydrogel的准备条件,并且验证了那补充说非可能减解的材料PNIPAAm能推迟降级哈更有效地比可能减解的材料MC。与5kGy剂量放射准备的PNIPAAm,MBAAm/NIPAAm(M/M)=0.015,单体concentration=3%与最慢酶的biodegradability生产了XLHA-PNIPAAm。DSC结果证明XLHA-PNIPAAm的温度敏感比XLHA-MC的更稳定。二合成hydrogels在cytotoxicity和溶血测试被限制,XLHA-PNIPAAmhydrogel的biocompatibility比XLHA-MChydrogel更好出现了。
简介:DearSir,IamDrKatrinaA.Mears,fromtheDepartmentofOphthalmologyandVisualSciences,UniversityofIowaCarverCollegeofMedicine,200HawkinsDrive,IowaCity,Iowa,USA.Iwishtopresentacaseofendophthalmitissecondarytoglobepenetrationfromahydrogelscleralbucklewhich,tothebestofourknowledge,isthefirstreportedcase
简介:Poly(vinylalcohol)(PVA)/hydroxyapatite(HA)compositehydrogelspecimenswerepreparedwith15%PVAand1%,2%,3%,4%and5%HAbyrepeatedfreezing-thawing.ThetestsofstaticanddynamicmechanicalpropertieswerecarriedouttodiscusstheinfluenceofdifferentcontentsofHAandfreezing-thawingcyclesonthemechanicalpropertiesofPVA/HAcompositehydrogel.TheresultsofstaticmechanicaltestsshowedthatthePVA/HAcompositehydrogelwith3%HAandninefreezing-thawingcycleshadexcellentstressrelaxationproperties,higherrelaxationratio,lowerstressequilibriumvalueandpresentedbetterpropertiesofcreepandrecovery.TheresultsofdynamicmechanicaltestshowedthatthePVA/HAcompositehydrogelwithninefreezing-thawingcycleshadhigherstoragemodulusandlossmodulus,sowasthePVA/HAcompositehydrogelwith3%HA.
简介:Thehydrogelwounddressingbasedonpolyvinylalcohol(PVA)waspreparedbythefreezing-thawingcyclicmethod.Thedehydrationkineticsofpreparedhydrogelswasdeterminedusingtheexperimentalmethodandmathematicalmodelingbasedondiffusionmechanism.TheresultsshowthatthedehydrationrateofPVAhydrogelwounddressinginverselydependsonthehydrogelthicknessaswellaswatercontentofthewound.Ontheotherhand,theinitialwatercontentofhydrogelandtheatmospherichumidityhavelittledirecteffectonthedehydrationrate.Thegoodagreementbetweenexperimentalandmathematicalmodelingresultsinearlystagesofdehydrationprocessshowsthatthepredominatefactordeterminingthedehydrationofthesewounddressingsisdiffusion.
简介:WithN-vinyl-2-pyrrolidone(NVP)anditaconicacid(IA),poly(N-vinyl-2-pyrrolidone/itaconicacid)[P(NVP/IA)]hydrogelwassynthesizedbyfreeradicalsolutionpolymerization.ThestructureofthisP(NVP/IA)wascharacterizedbyIR.Effectsofconcentrationofitaconicacid,amountofcross-linkagent,N,N′-methylene-bis-acrylamide,reactiontemperature,andtimeonpropertiesofswellingratio(SR)ofthehydrogelwereinvestigated.Theresultsshowthatthebestswellingpropertyofthehydrogelisobtainedat50℃and1.5h.pHsensitivityincreasesastheconcentrationofitaconicacidinthehydrogelsystemincreases.Swellingratioofthehydrogeldecreasesastheamountofcross-linkagentincreases.
简介:Poly(vinylalcohol)/hydroxylapatite(PVA/HA)compositehydrogelwaspreparedbyrepeatedfreezingandthawing.Thewaterlosspropertiesoftheresultanthydrogelwereinvestigatedbyusingopticalmicroscope.LongtimeimmersiontestsofPVA/HAcompositehydrogelwerecarriedoutinthedilutedcalfserumsolutiontostudythechangelawsofswellingpropertieswiththefreezing-thawingcyclesandHAcontent.Themicro-morphologiesofPVA/HAcompositehydrogelafterlongtimeimmersionwereobservedbymeansofthehigh-accuracy3Dprofiler.TheresultsshowthattheswellingprocessofPVA/HAcompositehydrogelistheconverseprocessofitswaterloss.LongtimeswellingratiocurvesofPVA/HAcompositehydrogelinthecalfserumsolutionaremanifestedasfourstagesofquickincrease,decrease,slowdecreaseandstablebalance,anditsequilibriumswellingratiodecreaseswiththeincreaseoffreezing-thawingcyclesandHAcontent.ItisrevealedthatthenetworkstructureofthecompositehydrogelimmersedforalongperiodissignificantlyimprovedwiththeincreaseofHAcontent.PerfectnetworkstructuresofPVA/HAcompositehydrogelaswellasfullandequilibriumtissuesafterswellingequilibriumareobtainedwhentheHAcontentis3%andthenumberoffreezing-thawingcyclesis7.