简介：在这份报纸，有在风险上并且随着时间的过去的依赖结构的一种类型的多维的可靠模型被考虑。借助于设计方法，不同类、同类的B

简介：InMarch2017,NarendraModiledhisBharatiyaJanataParty(BJP)tovictoryinstateelections,amongwhichhegainedparliamentaryelectionofUttarPradesh(stateinnorthernIndia),knownastheweathervaneofIndianelections.Backin2014,theBJPhadalreadywonasimplemajorityinLokSabha(thelowerhouseofparliament),bringinganendtomorethan30yearsofcoalitiongovernment.Now,theBJPisexhibitingstrongerpresenceasaone-party-ruleatbothfederalandlocallevels,withnocounter-balancefromtheIndianNationalCongress,localparties,orleftwingpartiesnoworintheforeseeablefuture.ThisincreasesthelikelihoodofModi'sre-electionasprimeministerin2019.Obviously,Indianpoliticaldevelopmentischaracterizedbycomplexity,accidentalfactorsandintrinsiclogic,whichwilldefinitelyexertgreatinfluenceonthefutureofIndia.

简介：在这份报纸，我们考虑从消费者收集使用的产品并且生产重新生产的产品的生产仅仅新的产品和一个制造商的由一个原来的制造商(OM)组成的一个单个时期的模型。OM和制造商在产品市场竞争。我们作为一个工具检验政府津贴的效果支持重新生产的活动。在里面特别地，我们认为三是津贴选择：到制造商，到消费者的津贴，和津贴的津贴由制造商和消费者分享了。我们发现制造商或消费者上的政府津贴的介绍总是增加重新生产的活动。我们也发现因为到制造商的津贴导致重新生产的产品的更低的价格，到制造商的那津贴是最好的津贴选择，因此导致更高级的消费者剩余。

简介：Theionsaturationcurrentisveryimportantinprobetheory,whichcanbeusedtomeasuretheelectrontem-peratureandthefloatingpotential.Inthiswork,theeffectsofenergeticionsontheionsaturationcurrentarestudiedviaparticle-in-cellsimulations.Itisfoundthattheenergeticionsandbackgroundionscanbetreatedseparatelyasdifferentspecies,andthevsatisfytheirindividualBohmcriterionatthesheathedge.

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简介：Two-dimensional(2D)equationsformultiferroic(MF)laminatedplateswithimperfectinterfacesareestablishedinthispaper.Theinterfacebetweentwoadjacentsublayers,whicharenotperfectlybondedtogether,ismodeledasageneralspring-typelayer.Themechanicaldisplacements,andtheelectricandmagneticpotentialsofthetwoadjacentlayersareassumedtobediscontinuousattheinterface.Asanexample,theinfluencesofimperfectinterfacesonthemagnetoelectric(ME)couplingeffectsinanMFsandwichplateareinvestigatedwiththeestablished2Dgoverningequations.NumericalresultsshowthattheimperfectinterfaceshaveasignificantimpactontheMEcouplingeffectsinMFlaminatedstructures.

简介：这研究的目的是提供quantificational关于一个统一索引的损坏霜的水泥的力量，僵硬，和变丑能力的变化法律，数据被不同研究人员获得。然后，相对压缩力量(RCS)的索引作为霜损坏和测试损坏霜的水泥的数据的很多机械表演的指示物被介绍被收集并且分析。由曲线适合，在RCS和起始的橡皮之间的关联模量，紧张在达到顶点压缩应力，和biaxial压缩强度，和张力的强度，和紧张在达到顶点张力的应力被建立。此后，在装载的monotonic下面的损坏霜的水泥的分析压力紧张反应用RCS并且与试验性的数据的相比被介绍。而且，损坏霜的水泥的一个各向同性的elastoplastic损坏模型使遭到了到装载重复被建立。最后，我们能系统地在水泥的机械表演上估计霜损坏的效果，它能被为损坏霜的水泥的数字模拟提供结构。

简介：数字模拟被执行调查云冷凝作用原子核(CCN)的效果microphysical过程和下得很大的冰雹的降水特征上的集中。二个下得很大的冰雹案例被模仿，一个春天案例和一个夏天案例在北中国的一个半干旱的区域，与地区性的大气的建模系统。结果被用来调查在春天和夏天下得很大的冰雹之间的CCN效果的差别和类似。类似是：(1)当混合比率的全部的冰阶段提高时，混合比率的全部的hydrometeor减少，与增加CCN集中；(2)CCN集中的改进导致小型的hydrometeor粒子，但是一减少大尺寸的hydrometeor粒子的更大的数量的生产；(3)当CCN集中增加，supercooled云水和雨水做更小的贡献下冰雹，当时冰阶段hydrometeors在冰雹的生长呈现活跃角色；(4)当CCN集中增加时，当相对，角色与冰阶段降水的相比在全部的降水还原剂的数量由液体阶段降雨玩了时，全部的降水的数量减少。二暴风雨之间的差别包括：(1)CCN集中的增加趋于减少在春天案例中混合比率的太古的冰，但是在夏天案例中提高他们；(2)冰阶段hydrometeor粒子贡献更多在春天盒子中招呼生长，当液体水在夏天盒子中更作出贡献时；(3)CCN集中的增加在不同季节在表面冰雹降水上有不同效果。

简介：高效率的优点，低SFC(特定的燃料消费)，超离频绕过比率扇涡轮引擎吸引越来越多的注意在现代广告引擎。中间的汽轮机管(ITD)它高连接有低压力的压力汽轮机(HPT)汽轮机(并行口)，由指导流动没有太多损失，从HPT来到并行口在汽轮机的全面表演上有批评影响。因此，掌握设计好攻击的、甚至超级好攻击的ITD的技术变得越来越迫切。更多担心被专注于管。然而，改进汽轮机以便推进，并行口嘴被排列成ITD弄短低压力轴。与如此的设计概念，那块并行口嘴流动地被在上游的管结构容易影响，是明显的，但是相反收到少得多兴趣。在这份报纸，数字方法被用来调查一些ITD的效果与在上游打漩并行口上的片嘴。有一样的九个模型打漩并且嘴片当ITD的长度是唯一的时要换掉的参数，将被讨论。最后，为设计者的几个结论和忠告被总结。在改变管，入口和插头的轴的长度以后，嘴的流动地相应地不同。在另一方面，表面介绍的嘴片(吸和压力)上的砍的压力在各种各样的入口流动下面的单个特征。除了那，像计时的效果在这份报纸被描述，它将贡献大部分到压力损失并且应该被付足够的注意。

简介：AIMTo评估穿二种不同类型的新keratoconus病人的角膜的房间形态学僵硬气体可渗透(RGP)为1y.METHODSThirty的隐形眼镜39个新keratoconus病人的九只眼睛与二被选择并且随机适合RGP隐形眼镜的类型。组1有21只眼睛与常规僵硬气体可渗透(RRGP)18看的接触透镜和休息在与的组2特殊设计了僵硬气体可渗透(SRGP)接触透镜。角膜的房间形态学用在没有透镜扫描共焦的显微镜的一个裂缝被评估穿并且在接触透镜在组1穿的接触透镜wearing.RESULTSAfter1y的1y以后，吝啬的前面、以后的stromalkeratocyte密度是显著地少些(P=0.006和P=0.001，分别地)与没有透镜相比穿。前面、以后的stromalkeratocyte的吝啬的房间区域也是显著地不同的(P=0.005和P=0.001)从没有透镜穿。前面、以后的stromal薄雾增加了18.74%和23.81%，分别地在接触透镜穿的1y以后。而在组2，统计上重要的变化仅仅在房间密度与前面的基质的区域被观察(P=0.001和P=0.001，分别地)在1y以后。当时，前面、以后的stromal薄雾的水平在接触透镜穿的1y以后增加了16.67%和11.11%。Polymegathism和多形性也在接触透镜groups.CONCLUSIONConfocal显微镜学观察显示出的接触透镜在两个穿的1y以后增加了在在特别穿隐形眼镜的keratoconic角膜的角膜的房间形态学的重要改变组织1。接触透镜的类型必须小心地被选择在角膜的房间形态学最小化变化。

简介：Weconsideraquantumparticleasawavepacketinthecoordinatespace.Whentheconjugatewavepacketinthemomentumspaceisconsidered,wefindthatthegroupvelocitiesofthesetwowavepackets,whichdescribetheparticledynamics,areinagreementwiththeHamiltonequationsonlyifinthetimedependentphasesoneconsiderstheLagrangianinsteadoftheHamiltonianwhichleadstotheconventionalSchr?dingerequation.Wedefinearelativisticquantumprincipleassertingthataquantumparticlehasafinitefrequencyspectrum,withacutoffpropagationvelocitycasauniversalconstantnotdependingonthecoordinatesystem,andthatanytimedependentphasevariationisthesameinanysystemofcoordinates.Fromthetimedependentphaseinvariance,therelativistickinematicsisobtained.Weconsidertwotypesofpossibleinteractions:1)Aninteractionwithanexternalfield,byamodificationofthetimedependentphasedifferentialwiththetermsproportionaltothedifferentialsofthespace-timecoordinatesmultipliedwiththecomponentsofthisfieldfour-potential,and2)aninteractionbyadeformationofthespace-timecoordinates,duetoagravitationalfield.Fromtheinvarianceofthetimedependentphasewithfieldcomponents,weobtainamechanicalforceoftheformofLorentz’sforce,andthreeMaxwellequations:TheGauss-Maxwellequationsfortheelectricandmagneticfluxes,andtheFaraday-Maxwellequationfortheelectromagneticinduction.Whenthefourthequation,Ampère-Maxwell,isconsidered,theinteractionfieldtakestheformoftheelectromagneticfield.Foralowpropagationvelocityoftheparticlewaves,wegetapacketofwaveswiththetimedependentphasesproportionaltotherelativisticHamiltonian,asinDirac’sfamoustheoryofspin,andaslowly-varyingamplitudewithaphaseproportionaltothemomentumandthisvelocity.Intheframeworkofourtheory,thespinisobtainedasanallquantumeffect,withoutanyadditionalassumptiontothequantumtheory.When

简介：Theeffectsofgaincompressiononthemodulationdynamicsofanopticallyinjectedgainleversemiconductorlaserarestudied.Calculationsrevealthatthegaincompressionisnotnecessarilyadrawbackaffectingthelaserdynamics.Withapracticalinjectionstrength,ahighgainlevereffectandamoderatecompressionvalueallowustotheoreticallypredictamodulationbandwidthfourtimeshigherthanthefree-runningonewithoutagainlever,whichisofparamountimportanceforthedevelopmentofdirectlymodulatedbroadbandopticalsourcescompatiblewithshort-reachcommunicationlinks.

简介：Strokeremainsthethirdleadingcauseofdeathandofadultdisabilityworldwide.Vascularocclusion,followedbyischemiccascade,leadstoirreversibletissueinjury.RecombinanttissueplasminogenactivatoristheonlyFDAapproveddrugforthecurrenttreatmentofacuteischemicstroke.However,traditionalChinesemedicinehasalonghistoryandrichclinicalexperienceinthetreatmentandrehabilitationofischemicstroke.Usingaclassicalmiddlecerebralarteryocclusion(MCAO)strokemodel,wetestedtheeffectivenessofYiqihuoxuecalmwind(YCW)capsuleonneurologicalfunction,grosspathologyandoxidativestressstatusinMCAOrats.YCWcapsule(3.36and6.72g·kg~(-1)ofcrudedrug)couldsignificantlylowerLonga'sscoreandsuperoxidedismutase(SOD)level,togetherwithlessnecroticcellsandinfarctedarea.InadditiontoelevatedMDAanddownregulatediNOSexpression,YCWcapsuleexhibiteditsneuroprotectiveeffectsviafreeradicalscavengingandNOinhibition.

简介：Background:ThefragilelandscapesoftheHimalayanregionarehighlysusceptibletonaturalhazards,andthereisongoingconcernaboutcurrentandpotentialclimatechangeimpacts.ThisstudyprovidesbackgroundinformationonIndia'sWesternHimalayasandreviewsevidenceofwarmingaswellasvariabilityinprecipitationandextremeevents.Methods:UnderstandingandanticipatingtheimpactsofclimatechangeonHimalayanforestecosystemsandtheservicestheyprovidetopeoplearecritical.Effortstodevelopandimplementeffectivepoliciesandmanagementstrategiesforclimatechangemitigationandadaptationrequiresparticularnewresearchinitiatives.Thevariousstudiesinitiatedandconductedintheregionarecompiledhere.Results:SeveralnewinitiativestakenbytheHimalayanForestResearchInstituteinShimlaaredescribed.Thisincludesnewpermanentobservationalfieldstudies,somewithmappedtrees,inhighaltitudetransitionalzonesforcontinuousmonitoringofvegetationresponse.WehavealsopresentednewstrategiesformitigatingpotentialclimatechangeeffectsinHimalayanforestecosystems.Conclusions:AssessmentoftheecologicalandgeneticdiversityoftheHimalayanconifersisrequiredtoevaluatepotentialresponsestochangingclimaticconditions.Conservationstrategiesfortheimportanttemperatemedicinalplantsneedtobedeveloped.TheimpactofclimatechangeoninsectsandpathogensintheHimalayasalsoneedtobeassessed.Coordinatedeffortsarenecessarytodevelopeffectivestrategiesforadaptationandmitigation.

简介：BackgroundEnd阶段脚关节关节炎损害联合功能和病人活动性。全部的脚关节代替是一个外科的过程对待严重脚关节关节炎。SaltoTalaris解剖脚关节TM(STAA)被设计模仿正常脚关节解剖和脚关节运动的屈曲/扩展。这研究的目的是与结束阶段在gait.MethodsFive病人期间在脚关节关节功能和力学上检验STAA脚关节代替的效果单方的脚关节关节炎被招募。病人们执行了水平在2个场合上走在一个实验室背景，在以前并且在STAA脚关节手术以后的3个月。美国矫形的脚和脚关节社会(AOFAS)hindfoot分数被获得。A12照相机运动俘获系统被用来执行走的分析。步法temporo空间的参数和脚关节关节力学被评估。配对的学生t测试和非参量的Wilcoxon匹配测试被执行在在外科前和外科以后的走conditions.ResultsCompared之间的biomechanical变量检验差别到pre外科的条件，在3月post-STAA外科，病人们在AOFAShindfoot经历了更大的改进分数(p=0.0001)；STAA脚关节证明31%在脚关节关节旅行(p=0.045)增加，22%在脚关节plantarflexor时刻(p=0.075)增加，60%尽最大努力增加吸收(p=0.023)，并且68%尽最大努力增加生产(p=0.039)。病人们也证明26%在走速度(p=0.005)增加，迈进长度(p=0.013)的20%增加，在两倍支持时间(p=0.043)的15%减少，和在全部的位置的5%减少预定(p=0.055)在手术以后的.ConclusionThree月，STAA病人在脚关节功能和步法参数经历了改进。STAA脚关节在象走那样的每日的活动期间表明了改进脚关节力学。

简介：为了在压缩机的流动地上探索机翼探查试管和它的款项位置的效果，串联，并且发现机制怎么机翼探查影响压缩机串联的空气动力学的特征，这份报纸在一样的压缩机串联上执行了数字、试验性的工作。实验主要集中了于低马赫数字的案例(妈=0.1)，并且有不同马赫数字的案例(0.1，0.3，0.7)并且不同发生角度(-5,0，5)被数字方法调查。没有机翼探查试管的案例作为基线，和另外的三个案例被引用，机翼探查试管在不同chordwise位置安装了(30%，50%，70%弦长度)被学习。机翼探查试管的直径是3mm，它根据几何类似原则作为某特别机翼探查的300%扩大被设置。结果证明机翼探查试管根本在串联的流动能力上有否定影响调查点。分离和在压力方面上由机翼探查试管导致了的大规模streamwise旋涡在高马赫数字引起大多数损失。在压力方面表面的附近的流动领域上的机翼探查试管的影响是在低马赫数字的本地分离。机翼探查试管也有一清楚地在漏流动上完成。它减少漏流动的集体流动并且削弱漏旋涡的紧张，但是扩大影响区域。试管在chordwise位置通常是的一半被安装的盒子的全部的压力损失特别在高马赫数字比另外的盒子降低，它能甚至减少损失与基本盒子相比。

简介：Theaimofthismanuscriptistoreviewtheactionandadverseeffectsofcombinedoralcontraceptives(COCs)onoculartissues.Thepercentageofunwantedpregnanciesandthesubsequentabortionsmakecontraceptioncrucialworldwide.Over100millionwomenaroundtheworldusecommoncontraceptivemethods,includingintrauterinedevices,combinedestrogenandprogestinoralcontraceptives,aswellasprogestinonlypreparations(oralcontraceptives,implantsorinjections).COCsarewidelyusedforcontraception,buttheyarealsoindicatedinmenorrhagia,endometriosis,acneandhirsutism,fibroiduterusandpremenstrualsyndrome.However,theyhavebeenassociatedwithhighratesofcardiovascularevents,venousthromboembolicdisease,ischemicstrokesandbreastcancer.TheincidenceofCOCs-relatedocularcomplicationsisestimatedtobe1in230000,includingdryeyesymptoms,cornealedema,lensopacitiesandretinalneuro-ophthalmologicorvascularcomplications.WemayinferthattheseriousocularcomplicationsofCOCscanbepreventedbyeliminatingtheestrogendosageandchoosingthird-generationprogestins.Inanycase,doctorsshouldtakeintoconsiderationthesystemicandocularhistoryofthepatientsbeforeselectinganymethodofcontraception.

简介：Onetosixpercentofpatientswithmicroscopiccolitisarerefractorytomedicaltreatment.Theeffectoffaecalmicrobiotatransplantation(FMT)inactivecollagenouscolitis(CC)has,tothebestofourknowledge,neverbeenreportedbefore.Here,wereporttheeffectofrepeatedFMTinapatientwithCC.Thepatientpresentedwithseveresymptomsincludingprofusediarrheaandprofoundweightloss.Althoughsherespondedtobudesonideinthebeginning,shebecamegraduallyrefractorytomedicaltreatment,andwasthereforetreatedwithFMT.Thepatientremainedinremissionfor11moafterthethirdfaecaltransplantation.Theimmunomodulatoryeffectofthetherapywasevaluatedusingflowcytometry,whichshowedalterationsintheprofileofintraepithelialandlaminaproprialymphocytesubsetsafterthesecondtransplantation.OurobservationsindicatethatFMTcanhaveaneffectinCC,whichsupportthehypothesisthatluminalfactors,influencingtheintestinalmicrobiota,areinvolvedinthepathogenesisofCC.

简介：Background:Playersmaynotacquireadequatelevelsofmoderate-to-vigorousphysicalactivity(MVPA)whenplayingcommercialvideogames.Thisstudy’sgoalwastoevaluatetheeffectsofanexercisebikevideogameplayedbyusingamobileapplication-basedexergamethatwasdesignedexclusivelytopromoteparticipants’MVPA,withadditionalattentionpaidtothisgame’sabilitytopromotegreatersituationalinterest.Methods:Anexperimentaldesignwasusedwith163students(aged20.31±1.30,18–26years,61.3%male),allofwhomwererandomlyallocatedintoanexperimentalgroupandacontrolgroup.Physicalactivity(PA)levelswereassessedwithActiGraphGT3X+(ActiGraphInc.,FortWaltonBeach,FL,USA)accelerometers.Thesituationalinterestscalewasusedtoevaluatestudents’situationalinterestinbothgroups.Multivariateanalysisofvariancewasconductedtoexaminethedifferencesbetweensedentarybehavior,PAlevels,andsituationalinterestbetweengroups.Regressionanalyseswerealsoused,withthepurposebeingtoevaluatethestrengthoftherelationshipbetweenPAandsituationalinterest.Results:Resultsrevealedthattheexperimentalgrouphadhigherdegreesofsedentarybehavior,lightPA,totalinterest,instantenjoyment,explorationintention,attentiondemand,novelty,andchallenge,whereasthecontrolgroupreceivedhigherscoresforMVPA(control95.01%vs.experimentalgroup89.94%).Regressionanalysisindicatedthatinstantenjoyment(β=0.49,p<0.01),explorationintention(β=0.18,p<0.05),andattentiondemand(β=0.17,p<0.05)werepositivepredictorsfortotalinterest,explaining43%ofitsvariance.Conclusion:Anewlydesignedmobileapplication-basedexergameplayedviaanexercisebikemayenhancesituationalinterestandprovideadecentlevelofPAforplayers.

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