简介：Thispaperanalysestheanteriordescendingbranchofthearteriacoronariasinistrafromtheviewofhemodynamics.Theresultsshowthatthebranchingoftheanteriordescendingbranchwithanangleof90°attheopeningandtheformationofthemuralarteriacoronariaarethehemodynamiccharacteristics.Theshearingstressoftheturbulentflow,theadditionalpressure,theformationofthebloodvertex,andtheimpulsivepressure,causedbythesecharacteristics,arehemodynamicreasonsthatleadstotheoccurenceofatherosclerosisinanteriordescendingbranch.

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简介：基于卫星雷达的工作原则，地震变丑地由interferometric测量了合成的孔(InSAR)地面排水量的设计在卫星的视觉(LOS)的线与seismogenic差错被联系。然而，LOS设计是复杂的，并且不仅与上升/下降的模式和SAR数据的发生角度有关，而且与罢工和差错的运动感觉有关。甚至为一样的地震，从不同上升/下降的数据导出的LOS变丑能是几乎在另一种情况中在一种情况中相同，却相当不同，它与域观察做InSAR地震变丑和它的比较的解释困难。在这研究，我们拿了在罢工，差错运动感觉，和上升/下降的模式，以及3D变丑回答的InSAR和差错的LOS观察敏感之间的关系的定量分析。我们用上升/下降模式在地震的不同类型学习了LOS变丑领域的特征和差别，与为地震的一种罢工滑倒类型的关系的特别地详细的分析。我们也与不同罢工和最佳的观察数据模式总结了差错的LOS变丑领域的特征。作为例子拿罢工滑倒Yushu地震和正常Gaize事件，我们使用了上升/下降的模式的SAR数据验证量的计算的结果。这些分析愿望不仅提供InSAR地震变丑领域的更合理的解释并且而且帮助理解数据与不同观察模式揭示的地震变丑领域的差别，因此在地震学支持InSAR技术的应用程序。

简介：Purpose：Theaimofthisstudywastoextendcurrenthalf-sarcomeremodelsbyinvolvingarecentlyfoundforce-mediatedactivationofthethickfilamentandanalyzetheeffectofthismechanosensingregulationonthelengthstabilityofhalf-sarcomeresarrangedinseries.Methods：Weincludedasuper-relaxedstateofmyosinmotorsanditsforce-dependentactivationinaconventionalcross-bridgemodel.Wesimulatedactivestretchesofasarcomereconsistingof2non-uniformhalf-sarcomeresonthedescendinglimboftheforce-lengthrelationship.Results：Themechanosensingmodelpredictsthat,inapassivesarcomereonthedescendinglimboftheforce-lengthrelationship,thelongerhalf-sarcomerehasahigherfractionofmyosinmotorsintheon-statethantheshorterhalf-sarcomere.Thedifferenceinthenumberofmyosinmotorsintheon-stateensuresthatuponcalcium-mediatedthinfilamentactivation,theforce-dependentthickfilamentactivationkeepsdifferencesinactiveforcewithin20%duringanactivestretch.Intheclassicalcross-bridgemodel,thecorrespondingdifferenceexceeds80%,leadingtogreatlengthinstabilities.Conclusion：Oursimulationssuggestthat,incontrasttotheclassicalcross-bridgemodel,themechanosensingregulationisabletostabilizeasystemofnon-uniformhalf-sarcomeresarrangedinseriesonthedescendinglimboftheforce-lengthrelationship.

简介：Inanerawhencardiactransplantpatientsaresurvivingmoreimmediateissuesofrejectionandinfection,theprevalenceofmorechronicissuessuchascardiacallograftvasculopathy(CAV)isrising.Thiscasedescribesaman20yearsaftercardiactransplantwithhisfirstpresentationofCAV.Acutemyocardialinfarctionwasdiagnosedonthebasisofsymptomsandbiochemicalmarkersandoncoronaryangiography,andhewasfoundtohaveacriticalstenosisofthemidportionoftheleftanteriordescendingartery.Itwaselectedtotreatthispercutaneouslywithafullybioresorbablevascularscaffold(BVS)becauseofthediffusenatureofthediseaseprocess.Thiswassuccessfullyperformedwithopticalcoherencetomographyguidance.TheuseofBVSinCAVhasnotbeenwellstudied.ThisisoneoffewcasereportsdescribingtheuseofBVSinCAV.

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简介：IntroductionMyocardialischemiaandanginapectoriscanbecausedbyvariousmechanismssuchascoronaryatherosclerosis,vasospasmorcoronarymicrovasculardysfunction[1].Weherereportacaseofa56-year-oldfemalepatientwithahistoryofpreviouspercutaneouscoronaryinterventions(PCI)whoreportedrepetitiveattacksofrestingangina.Coronaryriskfactorsincludedhypertension,hypercholesterolemia(LDL=97mg/dLonatorvastatin),ex-smoker(ceased2013),andapositivefamilyhistory(fatalmyocardialinfarctioninfatheraged52yearsandbrother59years).