简介：Toinvestigatetheinhibitingeffectsoftheanti-angiogenicfactorandostatinandtheanti-angiogenicdrugendostatinontumourangiogenesisandtumourcells,acoupledmathematicalmodeloftumorangiogenesiswithtumourgrowthandbloodperfusionisdeveloped.Simulationresultsshowthatangiostatinandendostatincanimprovetheabnormalmicroenvironmentinsidethetumourtissuebyeffectivelyinhibitingtheprocessoftumorangiogenesisanddecreasingtumourcells.Thepresentmodelcanbeusedasavalidtheoreticalmethodintheinvestigationofthetumouranti-angiogenictherapy.
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