简介：

简介：三倍的螺旋状的结构的热稳定性在骨胶原生合成，功能和降级起一个关键作用。CD技术被利用描绘合成骨胶原的热稳定性模仿肽。因为它的便宜乐器学，低操作费用，容易的操作，和高敏感，荧光光谱学广泛地全世界与容易的存取被使用。这里，我们开发了一个其他的荧光方法检测骨胶原的热稳定性模仿肽。我们证明了那荧光光谱学能测量骨胶原的热稳定性在不同情形下面与低集中模仿肽。自我熄灭的试金将极大地帮助的这高度敏感的荧光骨胶原的性质模仿的顺序依赖者的研究肽，和它在决定象骨胶原，collectins，adiponectin，巨噬细胞scavenger和C1q那样的三倍的螺旋系统的热稳定性的应用程序有大潜力。

简介：Theinvitroandinvivoeffectsofcornpeptides(CPs)preparedfromcornglutenmealbyproteolysiswithanalkalineproteaseandfractionsofCPsfromSephadexG-15andG-10columnsonactivitiesofalcoholdehydroge-nase(ADH)werestudied.TheresultsshowthatCPsandfraction3ofCPsfromSephadexG-10columnenhanceinvitroADHactivity.Furthermore,theinvitroacceleratingeffectofthefraction3ofCPsonADHactivitywassuperiortothatofglutathione,whichwasalsofoundeveninthepresenceofADHinhibitor,suchaspyrazole.Intheinvivoexperiments,theanimalswerefedwithdifferentdosagesofCPsandwithadoseofChinesedistilledspiritorally,andsacrificedforthemeasurementofADHactivity.InvivoexperimentalresultsindicatethatCPSenhancedhepaticADHactivities.TotestthesafetyofCPsashealthfood,30dfeedingtestwasperformed.NoobvioustoxiceffectsweredetectedintreatedWistarrats.

简介：Stablesilvernanoparticleswassuccessfullysynthesizedbychemicalreductionofsilvernitrateinanionicliquid,1-n-butyl-3-methylimidazoliumtetrafluoroborate([BMIM]·BF4)atroomtemperature.ResultsofUV-Visdiffusereflectancespectroscopyshowas-preparedAgnanoparticlesexhibitatypicalemissionpeakat400―430nm.Byvaryingthereactiontemperatureandtheprecursorconcentration,thesizeandtheshapeofthesilvernanoparticlescouldbeeasilycontrolledundermildconditions.Analysesoftransmissionelectronmicrographs,X-raydiffractionpatternandX-rayphotoelectronspectrumfurtherrevealthatthesilvernanoparticleswerecoatedincompletelyby[BMIM]·BF4.Microbialexperimentsindicatethatas-preparedsilvernanoparticlesshowawidespectrumofantimicrobialactivitiesandhavebetterantimicrobialactivitiestoPseudomonasaeruginosathansilvernitratewiththesameconcentrationofsilver.

简介：benzothiazole衍生物的新系列被设计并且综合。最新综合的混合物对Escherichiacoli，葡萄球菌aureus和杆菌仙影拳为他们的抗菌剂活动被屏蔽。混合物6j和6o对E显示出最高的活动。coli和S。aureus。这些混合物的抗真菌的活动也对Candidaalbicans和曲霉属菌fumigatus被测试293。混合物4c，4g和6j对C展出了最高的活动。albicans。另外，混合物4a和6j对A显示了有希望的活动。fumigatus293。而混合物4a，6j和6p显示出中等活动，一样的混合物对ChromobacteriumviolaceumATCC12472为他们的察觉到antiquorum活动被检验。在里面综合混合物测试的vitrocytotoxicity对颈的癌症(Hela)和肾成纤维细胞癌症(COS-7)房间被执行线。结果显示所有测试混合物有IC50价值>50 ；对两根房间线的mol/L。分子的性质，毒性，药相似，和药获得混合物4a-c，5a，6g，h，6j，6l，6o和7c的侧面，d也被估计。

简介：Itwasfoundthatphosphorylationofsmallpeptidecouldimprovethesensitivityinmassspectrometry.DensityfunctionaltheorycalculationsshowedthattheenergyfortheprotonationofN-(O,O′-dimethyl)phosphorylglycylglycineislowerthanthatofglycylglycine.Thesecouldhelptounderstandingtheexperimentalresults.

简介：

简介：

简介：Thisstudyaimsattheeffectsofanintakeoflowmolecularweightcornpeptides(LMCPs)preparedfromzeinonalcoholmetablisminrats.LMCPs(1.0g/kgbodyweight)in15%ethanol(10mL/kgbodyweight)weregiventoWisterratsbyintragastricgavage.Theassayofbloodethanolwasconductedbyusingtheenzyme-basedassaykit.Theaminoacidanalysiswasmadewithanaminoacidanalyzer.ThedataoftheanimalexperimentsshowedthatLMCPscouldacceleratethemetabolismofalcoholinrats.Inthecontrolgroup,thebloodethanolconcentrationreachedthemaximumlevelof(827.0±77.3)mg/Lafterethanolloadingfor30min,thengraduallydecreased.Incontrast,thebloodethanolconcentrationonlyreached(527.25±47.0)mg/Lafter30mininthegroupofLMCPstaken.TheseresultsindicatethatLMCPscoulddecreaseethanolconcentrationinbloodrapidly.