简介:Skiniscomposedofbothadermallayer-consistingprimarilyoffibroblasts,andmatrixmacromolecules(ECM)-andanepidermallayer-composingofepidermalcellscontainingkeratinfilamentsundergoingprogressivedifferentiationfromabasalproliferatinglayertoasurfaceconsistingofterminallydifferentiated,epidermalcellsthatprotecttheskinfromtheenvironment.