简介：Basedontherelaxationequationsdescribingthechemicalequilibrationofgluons,quarksandsquarksatfinitebaryondensityderivedfromtheJüttnerdistributionofpartons,withthehelpofarapidphasetransitionscenariofromquarkphasetohadronphase,wecalculatestrangenessproductioninthequarkphaseandhadronphase.ItisfoundthattheK^-/π^-ratioisenhancedtobelargerthanthatinppcollisionsbyaboutafactor3.

简介：原子磁性的回声光谱学(~1H-NMR)，同步荧光spectrometry(SFS)和钌离子催化的质子氧化(RICO)方法被用来在阿曼残余部分决定polyaromatic原子核的化学结构。~1H-NMR分析的结果证明在aromatics，树脂和沥青质单位的芳香的戒指的平均数字分别地是3.2，5.6和8.2。SFS被用来在残余部分，在aromatics的芳香的戒指的主要分发范围，树脂和沥青质调查芳香的戒指的分发分别地是3-4戒指，3-5戒指和超过5枚戒指。在残余部分的芳香的网络被氧化生产众多的羧基的酸。benzenepolycarboxylic酸的类型和内容benzenetricarboxylic酸，benzenetetracarboxylic酸，benzenepentacarboxylic酸和benzenehexacarboxylic酸例如酞酸酸，在核心揭示了芳香的原子核的压缩类型。联本基部分(BIPH)，压缩cata的部分(CATA)，压缩仙子的部分(仙子)和压缩索引(BCI)基于形成的benzenepolycarboxylic酸被计算。结果暗示在所有残余部分有更少的联本基类型结构。aromatics部分几乎由压缩cata的类型系统组成，并且，沥青质部分完全在树脂部分由压缩仙子的类型系统组成共存二种类型，此处压缩仙子的类型在压缩cata的类型上是占优势的。基于在学习，部件-aromatics,树脂和沥青质获得的分析结果-被给多半结构的模型。

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简介：正IcongratulatetheChineseAssociationforInternationalUnderstandingforallithasbeenabletoaccomplish-duringits30yearsofpublicdiplomacy-initsmissionto"LettheworldunderstandChina,andletChinaunderstandtheworld."

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简介：人工耳蜗的工作主要包括手术适应证的选择,手术,调机和言语康复.《中国听力语言康复科学杂志》2004年第三期转发了针对以上各方面制定规范和标准的《人工耳蜗植入工作指南》因不同人工耳蜗装置的材料和设计原理不同,其使用的调机硬件、软件不同,调机方法、调机过程和调机参数也不同.在中国,目前大部分病人使用的是Nucleus的人工耳蜗装置,大部分人工耳蜗中心使用的是Nucleus调机硬件、软件和调机方法.

简介：瞄准：同时决定本地化嘘在内的和鱼精朊人的精原核。方法：核心的Immunofluorescence嘘和鱼精朊和染色体16的端粒区域的荧光原位杂交在decondensed被估计人的精原核。结果：Immunofluorescent本地化嘘，鱼精朊1(PRM1)并且(PRM2)鱼精朊2在精原核与染色体16telomeric序列的荧光原位杂交本地化一起揭示了分离分布。对以后的戒指区域局部性的Histones(即精子原子体环)，而PRM1和PRM2看起来在整个全部原子核被驱散。结论：人的核心精子的合作本地化嘘有染色体16的telomeric区域的与进一个少些压缩的状态的特定的非鱼精朊区域的重组一致。

简介：Objective:Toreviewdevelopmentsinsoundprocessorsoverthepast30yearsthathaveresultedinsignificantimprovementsinoutcomesforNucleus~recipients.

简介：Objective:Neuronsinthecochlearnucleusshowdifferentresponsepatternstotheshorttonebursts.Becauseofthelimitationsofanimalexperiments,itishardtoexploretheprinciple.Therefore,usingamodeltosimulateCNneuronswillbeafeasibleway.Methods:Basedontheinitialmodelmentionedinthepreviousstudy,weproposedanimprovedCNmodelinMATLABR2012b.Results:Bymodifyingtheparametersofthemodelwefoundtheinterchangesamong"primary-like","chopper",and"onset"responsepatterns.Furthermore,wesimulatedthe"pauser"responsepatternbyaddinganextrainputinourmodel.Conclusion:TheresultsindicatethatthesynapticintegrationsandtheinputmodescangiverisetodifferentcharacteristicsofCNneurons,whicheventuallydeterminetheresponsepatternsofCNneurons.

简介：Toelucidatethemechanismofphotodynamicdamageofcells,theeffectofHPDpluslightontranscriptlonalectlvltyInthemucleusIsolatefromthenormalratliverwasstudiedinvitorby3H-UTPincorporationintoRNA.MeasurementsoffluorescencespectrumshowedthatHPDwasboundtothenucleusanditsfluorescenceIntensityIncreasedwiththeIncreaseofHPDconcentration.TheexperimentalresultsIndicatedthatnochangescouldbeobservedwheneitherHPDorlightwasusedalone.WhereasthenucleartranscriptionactivitywasfoundtobeinhibitedsignificantlybybothHPDandlighttreatment,andthedegreeofInhibitionwasdependentontheHPDconcentrationandthetimeofexposuretolight.Aftertreatmentby3μg/mlHPD,theinhibitionrateofthenucleartranscriptionactivitywas23%,45%,69%,80%and90%,respectivelyforlightexposureof2,5,10,20and30minutes.Ourresultssuggestedthatdose-dependentdecreasesinthenucleartranscriptionactivity,andmarkedinhibitionofthe

简介：AIM:Toinvestigatetheeffectandmechanismofstimulationofthehypothalamicparaventricularnucleuswithglutamateacidinratswithulcerativecolitis(UC).METHODS:Theratswereanesthetizedwith10%chloralhydrateviaabdominalinjectionandtreatedwithanequalvolumeofTNBS+50%ethanolenema,injectedintotheuppersectionoftheanuswiththetailfacingup.Colonicdamagescoreswerecalculatedafterinjectingacertaindoseofglutamicacidintotheparaventricularnucleus(pVN),andtheeffectofthenucleustractussolitarius(NTS)andvagusnerveinalleviatingUCinjurythroughchemicalstimulationofthepVNwasobservedinrats.ExpressionchangesofC-myc,Apaf-1,caspase-3,interleukin(IL)-6,andIL-17duringtheprotectionagainstUCinjurythroughchemicalstimulationofthepVNinratsweredetectedbyWesternblot.Malondialdehyde(MDA)contentandsuperoxidedismutase(SOD)activityincolontissuesofratsweremeasuredbycolorimetricmethods.RESULTS:ChemicalstimulationofthePVNsignificantlyreducedUCinratsinadose-dependentmanner.TheprotectiveeffectsofthechemicalstimulationofthepVNonratswithUCwereeliminatedafterchemicaldamagetothepVN.AfterglutamatereceptorantagonistkynurenicacidwasinjectedintothepVN,theprotectiveeffectsofthechemicalstimulationofthepVNwereeliminatedinratswithUC.AfterAVpVlreceptorantagonist([Deamino-penl,val4,D-Arg8]-vasopressin)wasinjectedintoNTSorbilateralchemicaldamagetoNTS,theprotectiveeffectofthechemicalstimulationofpVNonUCwasalsoeliminated.AfterchemicalstimulationofthepVN,SODactivityincreased,MDAcontentdecreased,C-mycproteinexpressionsignificantlyincreased,caspase-3andApaf-1proteinexpressionsignificantlydecreased,andIL-6andIL-17expressiondecreasedincolontissuesinratswithUC.CONCLUSION:ChemicalstimulationofthehypothalamicpVNprovidesaprotectiveeffectagainstUCinjuryinrats.HypothalamicpVN,NTSandvagusnerveplayk

简介：ObjectivesToinvestigatetheexpressionofhistamineH1receptors(H1R)inthevestibularnucleusofbrainsteminratsandtheroleofH1Rinmotionsickness(MS).MethodsAtotalof24healthySprague-Dawleyratsweredividedrandomlyintofourgroups(n=6each)whichdeterminediftheanimalswouldreceiveinductionofMSordrug(promethazine)treatment:MS(-)/Drug(-);MS(+)/Drug(-);MS(-)/Drug(+at0.25mg);andMS(+)/Drug(+).MSwasinducedbycomplexmotionstimulationandtheconditionedtasteaversionwasusedasabehavioralindicatorofMS.Thevolumeof0.15%sodiumsaccharinsolution(SS)intakewithin45minutesaftermotionstimulationwasmeasured.H1Rinthevestibularnucleuswasexaminedbyimmunofluorescencestaining.TheexpressionofH1Rproteininbrainstemtissueatvestibularnucleuslevelwasdetectedbywesternblot.ResultsThemeanSSintakevolumeintheMS(+)/Drug(-)group(8.8ml)wassignificantlylessthanthatoftheMS(-)/Drug(-)group(15.1ml)(P<0.01).ThemeanSSintakevolumeoftheMS(-)/Drug(+)group(14.8ml)wassimilartothatoftheMS(-)/Drug(-)group.ThemeanSSintakevolume(9.6ml)oftheMS(+)/Drug(+)groupwasmorethanthatoftheMS(+)/Drug(-)group(P<0.01),butlessthanthatoftheMS(-)/Drug(-)grouporMS(-)/Drug(+)group(P<0.01).ImmunofluorescencestainingshowedpositiveexpressionofH1Rinthevestibularnucleusofbrainstemandtheexpressionwasenhancedbymotionstimulation.WesternblotanalysisshowedthatH1Rproteinexpressedinthebrainstemtissueatvestibularnucleuslevelandtheexpressionalsoincreasedsignificantlyaftermotionstimulation.TheMS-inducedincreaseofH1Rwasnotaffectedsignificantlybypromethazine.ConclusionsH1RsexistinthevestibularnucleusinratsandH1Rexpressionisup-regulatedbymotionstimulation,butnotaffectedbypromethazine.ThefindingsindicatethatthehistaminergicsystemisinvolvedinMS.Promethazine,asanH1Rblocker,mayplayitsanti-MSrolebycompetingthebindingsiteon

简介：WehavedeliveredviralvectorscontainingeitherChop2fusedwithGFP,Channelrhodopsin-2(ChR2),orHalorhodopsin(HaloR)fusedwithmCherry(toformlightgatedcationchannelsorchloridepumps,respectively),intothedorsalcochlearnucleus(DCN).OnetoeighteenmonthslaterweexaminedtheCNandinferiorcolliculus(IC)forevidenceofvirallytransfectedcellsandprocesses.ProductionofChR2andHaloRwasobservedthroughouttheDCN.Rhodopsinlocalizationwithinneuronswasdetermined,withelongate,fusiformandgiantcellsidentifiedbasedonmorphologyandlocationwithintheDCN.ProductionofChR2andHaloRwasfoundatboththeinjectionsiteaswellasinregionsprojectingtoandfromtheDCN.LightdrivenneuronalactivityintheDCNwasdependentuponthewavelengthandintensityofthelight,withonlytheappropriatewavelengthresultinginactivationandhigherintensitylightresultinginmoreneuronalactivity.Transfectingcellsviaviraldeliveryofrhodopsinscanbeusefulasatracttracerandasaneuronalmarkertodelineatepathways.Inthefuturerhodopsindeliveryandactivationmaybedevelopedasanalternativetoelectricalstimulationofneurons.

简介：Ｇｒｏｕｎｄ－ｓｔａｔｅＰｒｏｐｅｒｔｉｅｓｏｆＤｏｕｂｌｙ－ｍａｇｉｃＮｕｃｌｅｕｓ１００Ｓｎ￥ＷｅｎＷａｎｘｉｎ；ＪｉｎＧｅｎｍｉｎｇａｎｄＺｈｏｎｇＪｉｑｕａｎＴｈｅｄｏｕｂｌｙ－ｍａｇｉｃｎｕｃｌｅｉ１００Ｓｎｗａｓｐｒｏｄｕ?..

简介：ＳｐｉｎＡｓｓｉｇｎｍｅｎｔｆｏｒＹｒａｓｔＬｅｖｅｌｓｏｆＯｄｄ－ｏｄｄ１６２ＬｕＮｕｃｌｅｕｓ￥ＺｈａｎｇＹｕｈｕ；ＺｈｏｕＸｉａｏｈｏｎｇ；ＺｈａｏＱｉｎｇｚｈｏｎｇ；ＳｕｎＸｉａｎｇｆｕ；ＬｅｉＸｉａｎｇｇｕｏ；ＧｕｏＹ?..

简介：Highspinstatesintheneutron-rich^108Runucleushavebeenstudiedthroughmeasuringpromptγ-raycoincidencesfollowingthespontaneousfissionof^252CfwiththeGammaspheredetectorarray.Theyrastbandhasbeenconfirmed.Theone-phononγ-vibrationalbandandthetwo-quasiparticlebandbasedonthe5^-levelhavebeenextendedupto13^+and15^-,respectively.Inaddition,twolevelsat1644.8keVand1826.5keVexcitationenergiesarenewlyidentifiedandproposedtobethemembersofatwo-phononγ-vibrationalband.Itisshownthatthe^108Runucleushastriaxialdeformationwithparametersβ2～0.29andγ=-22°fromthetotalRouthiansurfacecalculations.Theobservedbandcrossingintheyrastbandisduetothealignmentofapairofh11/2neutronsaccordingtothecrankedshellmodelcalculations.Thepossibleconfigurationforthetwo-quasiparticlebandhasbeendiscussed.

简介：BACKGROUND:ElectrophysiologycanprovetheintegrationofafferentinformationfromthestomachmeridianofFoot-Yangminginthenucleustractussolitarius(NTS)andobjectivelydescribethespecificassociationbetweenmeridianvesselsandZangFuorgans.OBJECTIVE:ToinvestigatetheeffectsofafferentinformationfromacupunctureatSibai(ST2)acupointonneuronaldischargeinratNTS.DESIGN,TIMEANDSETTING:Arandomized,controlled,animalexperimentwasperformedattheKeyLaboratoryofMeridian-VesselsandZangFuOrgans,TraditionalChineseMedicineUniversityofHunan,StateAdministrationofTraditionalChineseMedicine,andKeyLaboratoryofAcupuncture,Moxibustion,andtheBiologicalInformationofHunanHigherEducationInstitutes,betweenDecember2005andOctober2008.MATERIALS:Atotalof52SpragueDawleyrats,ofeithergender,aged4months,wereincludedinthisstudy.Acupunctureneedlesof0.32mm(diameter)×40mm(length)wereused.METHODS:Anextracellularrecordingprotocolwasapplied.TheSibai(ST2)acupointinthestomachmeridianofFoot-Yangmingwasusedasanacupuncturepoint(acupoint).Simultaneously,Dicang(ST4)andNetting(ST44)acupointsinthestomachmeridianofFoot-Yangming,Quanliao(SI18)acupointinthesmallintestinemeridianofHand-Taiyang,andanon-acupointlateraltoSibai(ST2)acupoint,wereselectedascontrols.TheSibai(ST2)acupointwasstimulatedfor30seconds,byhandacupuncturethroughtwirlingandrotating,todeterminetheneuronsrespondingtobodysurfacestimulationintheNTS.MAINOUTCOMEMEASURES:FrequencyofrespondingNTSneuronsafteracupunctureatfouracupointsincludingSibai(ST2),Dicang(ST4),Neiting(ST44)andQuanliao(SI18)andonenon-acupoint.RESULTS:ThefrequencyofrespondingNTSneuronswassignificantlyhigherafteracupunctureatSibaithanatcontrolsitesincludingtheDicang(ST4),Netting(ST44)andQuanliao(SI18)acupointsandatthenon-acupoint(P<0.01).ThefrequencyofrespondingNTSneuronsatDicang(ST4)andQuanliao(SI

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