简介:Oneofthemainconcernsinusingcommercialsoftwareforfiniteelementanalysesofdam-foundation-reservoirsystemsisthatthesimplifyingassumptionsofthemasslessfoundationareunreliable.Inthisstudy,anappropriatedirectfiniteelementmethodisintroducedforsimulatingthemass,radiationdampingandwavepropagationeffectinfoundationsofdamfoundation-reservoirsystemsusingcommercialsoftwareABAQUS.Thefree-fieldboundaryconditionisusedformodelingthesemi-infinitefoundationandradiationdamping,whichisnotabuilt-inboundaryconditioninmostoftheavailablecommercialsoftwareforfiniteelementanalysisofstructuressuchasANSYSorABAQUSandthusneedstobeimplementeddifferently.Thedifferentmechanismformodelingofthefoundation,earthquakeinputandfar-fieldboundaryconditionisdescribed.Implementationofthefree-fieldboundaryconditioninfiniteelementsoftwareisverifiedbycomparingitwithanalyticalresults.Toinvestigationthefeasibilityoftheproposedmethodindam-foundation-reservoirsystemanalysis,aseriesofanalysesisaccomplishedinavarietyofcasesandtheobtainedresultsarecomparedwiththesubstructuremethodbyusingtheEAGD-84program.Finally,themassedandmasslessfoundationresultsarecomparedanditisconcludedthatthemasslessfoundationapproachleadstotheoverestimationofthedisplacementsandstresseswithinthedambody.
简介:CHINAFOUNDATIONFORHUMANRIGHTSDEVELOPMENT(CFHRD)isanationalnon-governmentalorganizationWiththestatusoflegalentity.
简介:Inthispaper,thenonlinearcollapseoftheBOHAI-8pilefoundationjacketplatformhasbeenanalyzed.Theultimateloadandcollapseprocessoftwocomputationalmodelsofthestructurearegiven.Onemodelisoffixedsupportwhoselengthiseighttimesthepilelegdiameterandtheotherconsid-ersthenonlinearityofthesoil-pileinteraction.
简介:AbstractAs a foundation of life-science research and advancement, biobanking has played a critical role and made tremendous contributions to healthcare, biotechnology, disease control and prevention, as well as bio-conservation for the benefit of all humankind. This paper starts with a brief introduction of basic concepts, history, classification, and significance of biobanking, followed by a discussion on cryobiology fundamentals and key challenges faced by cryopreservation in biobanking. A special case discussion on the cryopreservation and biobanking of pathogenic microorganisms to meet both the unmet needs for biomedical research and the urgent demand for developing countermeasures against the ongoing coronavirus disease 2019 (COVID-19) pandemic is highlighted with insightful recommendations for future studies.
简介:AbstractSince the 1970s, electronic fetal monitoring (EFM) also known as cardiotocography (CTG) has been used extensively in labor around the world, despite its known failure to help prevent many babies from developing neonatal encephalopathy and cerebral palsy. Part of EFM’s poor performance with respect to these outcomes arises from a fundamental misunderstanding of the differences between screening and diagnostic tests, subjective classifications of fetal heart rate (FHR) patterns that lead to large inter-observer variability in its interpretation, failure to appreciate early stages of fetal compromise, and poor statistical modeling for its use as a screening test. We have developed a new approach to the practice and interpretation of EFM called the fetal reserve index (FRI) which does the following: (1) breaking FHR components down into 4 components, (heart rate, variability, accelerations, and decelerations); (2) contextualizing the metrics by adding increased uterine activity; (3) adding specific maternal, fetal, and obstetric risk factors. The result is an eight-point scoring metric that, when directly compared with current American College of Obstetricians and Gynecologists EFM categories, even in version 1.0 with equal weighting of variables, shows that the FRI has performed much better for identifying cases at risk before damage had occurred, reducing the need for emergency deliveries, and lowering overall Cesarean delivery rates. With increased data, we expect further refinements in the specifics of scoring that will allow even earlier detection of compromise in labor.
简介:当设计一个堆积基础时,否定皮肤磨擦(NSF)是重要问题之一。然而,为堆积基础在dragload和downdrag上装载顺序的影响很少被学习。在这份报纸,一个三维的数字模型用FLAC3D被建立。与模型测试的结果相比,确定的模型能被用来学习堆积基础的NSF。影响因素包括堆积的长度直径比率和堆积头负担和超载的装载顺序被讨论。病历用FLAC3D被分析。计算结果在对测量结果的好同意。dragload和downdrag被堆积头负担和超载的装载顺序显著地影响,这被结束。dragload和downdrag在堆积头负担以后在超载的条件下面到达最大的价值。
简介:Thespudcanfoundationhasbeenwidelyusedinoffshoreengineeringforjack-uprigs.However,'punchthrough'failureoftenoccurswhereastrongersoillayeroverlaysasoftersoillayer.Inthisstudy,spudcanpenetrationintodoublelayeredsoilsisinvestigatednumerically.Thesoilprofileissetupasastrongersoillayeroverlayingasoftersoillayer,withthesoilstrengthratio(bottomsoilstrength/topsoilstrength)variedfrom0.1to1.0(1meansuniformsoil).Thebearingbehaviourisdiscussedandthebearingcapacityfactorsaregivenforvariouscasesinvolvingdifferentlayerthicknessesanddifferentstrengthratiosofthetwoclaylayers.Thedevelopmentoftheplasticzonesandtheeffectofsoilselfweightonthebearingcapacityarealsodiscussed.Fromthisstudy,itisfoundthat,whenaspudcanisdistantfromthesoillayerboundary,thespudcancanbeanalysedwithsinglesoillayerdata.However,whenaspudcanbecomesclosertothesoilboundarylayer,theinfluenceofthelowersoftsoillayerissignificant,andthebearingcapacityofthespudcandecreases.Thecriticaldistanceisanindicationoftheoccurrenceof'punchthrough'failure.Thecriticaldistancebetweenthespudcanandthelayerboundaryislargerforaroughspudcanthantheoneforasmoothone,andthecriticaldistancedecreaseswithincreasingsoilstrengthratio.Thedepthofcavityformedduringinitialspudcanpenetrationdependsonthetoplayersoilstrength,soilstrengthratioandunitsoilself-weight,andthecavityaffectsthespudcanbearingbehaviouraswell.
简介:Thetransversevibrationofanaxiallymovingstringsupportedbyaviscoelasticfoundationisanalysedusingthecomplexmodalmethod.TheequationofmotionisdevelopedusingthegeneralizedHamiltonprinciple.Theexactclosed-formsolutionofeigenvaluesandeigenfunctionsareobtained.Thegoverningequationisrepresentedinacanonicalstatespaceformdefinedbytwomatrixdifferentialoperators,andtheeigenfunctionsandadjointeigenfunctionsareprovedtobeorthogonalwithrespecttoeachoperator.Thisorthogonalityisappliedsothattheresponsetoarbitraryexternalexcitationsandinitialconditionscanbeexpressedinmodalexpansion.Numericalexamplesarepresentedtovalidatetheproposedapproach.
简介:一系列2D模型测试被进行估计合成垂直防波提的基础稳定性。在这篇论文,从试验性的学习的结果与一个公式相连地被介绍估计基础的稳定性数字,它是为如此的结构的基础稳定性的评估的最重要的参数。有不同盔甲石头尺寸的合成防波提的稳定性上的波浪高度,波浪时期和城墙与外濠间之狭道宽度的影响被调查。45测试被执行盖住这些参数的影响。根据现在的研究,城墙与外濠间之狭道宽度是有关盔甲基础的侵蚀的一个重要参数。作为城墙与外濠间之狭道宽度增加,城墙与外濠间之狭道侵蚀的数量减少。比较在现在的学习和Kimura等建议的估计的稳定性数字的结果之间被做。(1994),它是Tanimoto的扩展公式。结果证明以后的公式低估稳定性数字。然而,由使用一个改进因素大约1.7米到Kimura等。公式,结果与现在的试验性的结果相关……