简介:AsreadersofCancerBiologyandMedicinewellknow,therehasbeenaseismicshiftinhumanmolecularbiologyoverthepastfewyears,asmomentousinitsownwayasthediscoveryofthedouble-helicalstructureofDNAbyWatsonandCrick60yearsago,theelucidationofthegeneticcodeshortlythereafter,theadventofrecombinantDNAandgenecloning
简介:SeveralARMAmodelingapproachesareaddressed.Inthesemethodsonlypartofacorrelationsequenceisemployedforestimatingparameters.Itissatisfying,ifthegivencorrelationsequenceisofrealARMA,sinceanARMAprocesscanbecompletelydeterminedbypartofitscorrelationse-quence.Butforthecaseofameasuredcorrelationsequencethewholesequencemaybeusedtore-ducetheeffectoferroronmodelparameterestimation.Inaddition,thesemethodsnowdonotguar-anteeanonnegativespectralestimate.Inviewoftheabove-mentionedfact,aconstrainedleastsquaresfittingtechniqueisproposedwhichutilizesthewholemeasuredcorrelationsequenceandguar-anteesanonnegativespectralestimate.