简介：<正>ChinesePresidentXiJinpingpaidstatevisitstofourCentralAsiancountriesnamelyKazakhstan,Kyrgyzstan,Turkmenistan,UzbekistanandattendedtheShanghaiCooperationOrganizationSummitinBishkek,KyrgyzstaninSeptember,2013.OnSeptember7,PresidentXideliveredaspeechatNazarbayevUniversity,duringwhichheputforwardtheimportantinitiativeofjointly

简介：AIM:Toinvestigateenoughvalidmeasurements(VMs)toassessliverfibrosisinchronichepatitisBpatients(CHB).METHODS:OnehundredandtwelveCHBpatients(25women,87men)withameanageof38.43yearsreceivedliverstiffnessevaluationsusingreal-timeshearwaveelastographyfor10VMs.Allpatientsunderwentliverbiopsy.Basedonthebiopsypathology,theliverstiffnessdataobtainedfromdifferentVMs(1,2,3,5and10times)werecomparedfortheevaluationofliverfibrosis.ThecorrelationbetweentheelasticmodulusmeansoftheliverobtainedfromdifferentVMsofdetectionateachpathologicalstagewasanalysed.Thereceiveroperatingcharacteristic(ROC)curvewasemployedtodeterminethediagnosticperformanceofdifferentVMsofdetection,andtheareasundertheROCcurveofdifferentgroupswerecompared.RESULTS:Theliverstiffnessvaluesobtainedfrom1VM,2VMs,3VMs,5VMsandall10VMsforstageF0were6.95±2.01kPa,6.87±1.83kPa,6.90±1.88kPa,6.95±1.93kPaand7.15±1.89kPa,respectively(F=0.043,P=0.996).ForstageF1,thesevalueswere7.12±1.72kPa,7.24±1.72kPa,7.21±1.74kPa,7.10±1.78kPaand7.04±1.70kPa,respectively(F=0.075,P=0.990).ForstageF2,theywere9.37±3.87kPa,9.18±3.68kPa,9.19±3.81kPa,9.18±3.81kPaand9.19±3.53kPa,respectively(F=0.012,P=1.000).ForstageF3,thesewere11.91±3.88kPa,11.78±4.04kPa,11.83±4.07kPa,11.94±4.17kPaand12.00±4.02kPa,respectively(F=0.010,P=1.000).ForstageF4,thereadingswere19.30±7.63kPa,19.40±7.36kPa,19.54±7.43kPa,19.73±7.21kPaand20.25±7.22kPa,respectively(F=0.054,P=0.995).Therewerenosignificantdifferencesbetweenthesegroups.Intraclasscorrelationcoefficientsamongdifferentpathologicalstages(F0-F4)withdifferentdetectionVMswere0.995,0.993,0.996,0.994and0.996,respectively.Themeanelasticityvaluesfrom1VM,2VMs,3VMs,5VMsand10VMscanaccuratelydistinguishfibrosisstages(F0vsF1234,F01vsF234,F012vsF34andF0123vsF4)withnosignificantdifferencesinthefivegroups(P>0.05forall).CONCLUSION:One