简介：AIM:Todeterminethecorrelationbetweenthehepaticvenouspressuregradientandtheendoscopicgradeofesophagealvarices.METHODS:FromSeptember2009toMarch2013,atotalof176measurementsofhepaticvenouspressuregradient(HVPG)weredonein146patients.EachtransjugularHVPGwasmeasuredtwice,firstusinganendwholecatheter(EH-HVPG),andthenusingaballooncatheter(B-HVPG).TheHVPGwascomparedwiththeendoscopicgradeofesophagealvarices(accordingtothegeneralrulesforrecordingendoscopicfindingsofesophagogastricvarices),whichwasrecordedwithinamonthofthemeasurementofHVPG.RESULTS:Thestudyincluded110menand36women,withameanageof56.1years(range,43-76years).Thetechnicalsuccessrateofthepressuremeasurementswas100%andtherewerenocomplicationrelatedtotheprocedures.MeanHVPGwas15.3mmHgasmeasuredusingtheendholecathetermethodand16.5mmHgasmeasuredusingtheballooncathetermethod.MeanHVPG(bothEHHVPGandB-HVPG)wasnotsignificantlydifferentamongpatientswithdifferentcharacteristics,includingsexandcomorbidfactors,exceptforcaseswithhepatocellularcarcinoma(B-HVPG,P=0.01;EH-HVPG,P=0.02).Portalhypertension(>12mmHgHVPG)occurredin66%ofpatientsaccordingtoEH-HVPGand83%ofpatientsaccordingtoB-HVGP,andsignificantlycorrelatedwithChild’sstatus(B-HVPG,P<0.000;EHHVGP,P<0.000)andesophagealvariesobserveduponendoscopy(EH-HVGP,P=0.003;B-HVGP,P=0.006).Onehundredandthirty-fiveendoscopieswereperformed,ofwhich15showednormalfindings,27showedgrade1endoscopicesophagealvarices,49showedgrade2varices,and44showedgrade3varices.WhencomparingendoscopicesophagealvaricealgradesandHVPGusingunivariateanalysis,thePvaluewas0.004forEH-HVPGand0.002forB-HVPG.CONCLUSION:BothEH-HVPGandB-HVPGshowedapositivecorrelationwiththeendoscopicgradeofesophagealvarices,withB-HVPGshowingastrongercorrelationthanEH-HVPG.