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简介：　　【摘 要】目的：观察单硝酸异山梨酯注射液对心肌梗死后并发症的临床疗效。方法：将 82例患者随机分为治疗组与对照组，每组 41例，治疗组使用单硝酸异山梨酯注射液 20mg混入 5%葡萄糖液 250ml中，静脉滴注，一日一次，连续使用 15天。对照组使用参麦注射液 60ml 混入 5%葡萄糖注射液 250ml中，静脉滴注，一日一次，并口服硝酸异山梨酯片 10mg，一日三次。结果：两组中，治疗组 41例，病死率为 4.8%；对照组 41例，病死率 12.2%。治疗组 41例，心绞痛发生率为 8%，心律失常发生率 5%；对照组 41例，心绞痛发生率为 39%。治疗组治疗效果明显高于对照组。结论：单硝酸异山梨酯注射液，能够有效的防治心肌梗死后并发症，防治冠心病心绞痛、心律失常等。具有起效快、疗效高、安全、不良反应少等特点，是一种安全有效的心血管药物，已成为治疗心血管疾病中的基本药物，在心肌梗塞后并发症中的常规用药。  　　【关键词】单硝酸异山梨酯注射液；心肌梗死；并发症；疗效  　 [Abstract] Objective: To observe the clinical effect of Isosorbide Mononitrate Injection on complications after myocardial infarction. Methods: 82 patients were randomly divided into treatment group and control group, 41 cases in each group. The treatment group was given Isosorbide Mononitrate Injection 20mg mixed with 250ml 5% glucose solution, intravenous drip, once a day, for 15 consecutive days. The control group was given Shenmai injection 60ml mixed with 250ml 5% glucose injection, intravenous drip, once a day, and oral isosorbide nitrate tablets 10mg, three times a day. Results: in the two groups, 41 cases in the treatment group, the mortality rate was 4.8%; 41 cases in the control group, the mortality rate was 12.2%. The incidence of angina pectoris and arrhythmia was 8% and 5% in the treatment group and 39% in the control group. The treatment effect of the treatment group was significantly higher than that of the control group. Conclusion: Isosorbide Mononitrate Injection can effectively prevent and treat the complications after myocardial infarction, coronary heart disease, angina pectoris and arrhythmia. It is a safe and effective cardiovascular drug. It has become the basic drug in the treatment of cardiovascular diseases and the conventional medication in the complications after myocardial infarction.

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