Changes of pulmonary intercellular adhesion molecule-1 and CD11b／CD18 in peripheral polymorphonuclear neutrophils and their significance at the early stage of burns-中国期刊网

摘要 Objective:Toinvestigatetheroleofintercellularadhesionmolecule-1(ICAM-1)intheaccumulationofpolymorphonuclearneutrophils(PMN)inthelungsattheearlystageofburns.Methods:Myeloperoxidasecontentinlungtissuesandbronchoalveolarlavagefluid(BALF)weredetected.ICAM-1anditsmRNAexpressioninlungtissuesweredeterminedbyimmunohistochemicalmethodandinsituhybridization.CD11b/CD18expressionontheperipheralPMNswasmeasuredbyflowcytometry.Results:ThelevelsofmyeloperoxidaseinlungtissuesandBALFafterburninjuryweremarkedlyhigherthanthoseofcontrol.ExpressionofICAM-1anditsmRNAinthelungtissuesandCD11b/CD18onperipheralPMNssurfacewassignificantlyincreasedat2,6,12,24hafterburns.Conclusions:PMNsaccumulationinthelungsisrelatedtoincreasedICAM-1expressiononpulmonarymicrovascularendothelialcellsandCD11b/CD18expressiononPMNattheearlystageofburninjury.

1黄谦1王义平1陈斯1邓烈华2. 中性粒细胞来源微粒AnxA1、CD11b及CD62L对烧伤脓毒症预后的关系.免疫学,2018-03.
2吴赛珠;刘建国;谭家余;周可祥;Gorge D Webb;隗和明;郭志刚. Effects of Estrogen Level on the Function of Vascular Endothelial Cells and Expression of Vascular Cell Adhesion Molecule-1(?).心血管疾病,2002-02.
3BAO,Daren. Relationship of plasma homocysteine,soluble intercellular adhesion molecule-1,high mobility group box 1 protein with carotid intima-media thickness in elderly patients with type 2 diabetes mellitus.,2023-03.
4樊都吴勇. 慢性阻塞性肺疾病患者CD11b表达的变化研究.免疫学,2013-11.
5贾卉娟,邓蓉,张解放,李凡民,孟鲁静,王东秋,王成敏. 外周血sTREM-1、IL-6及CD11b、CD62L在呼吸机相关性肺炎诊断中的价值分析.医药卫生,2020-09.
6何璐 Lars Dirckinck-Holmfeld 蔡荣林宋小鸽胡玲余爽张道琴. Effect of Moxibustion Therapy on the Serumal Intercellular Cell Adhesion Molecule and the Histopathology of Experimental Arthritis in Rats.中医学,2010-04.
7JI,busi,BU,Laike,ZHENG,Jieke. Changes and Significance of Cytokines in Serum of Rabbits with Acute Pulmonary Embolism.,2023-03.
8WANG Qian;SUN Shuyu;ZHAN Fengxia. Clinical Significance of Platelet Activation Glycoproteins GPⅡb/Ⅲa, CD62p and CD63 in Pregnancy- Induced Hypertension.公共卫生与预防医学,2005-04.
9ZHU Gui-ping;WANG Zhuo;LEI Da;LIN Zhong-wei. The correlations of carotid vascular remodeling with the inflammation biomarkers and adhesion molecule in peripheral blood monocytes in hypertensive patients with hyperhomocysteinemia.心血管疾病,2015-02.
10刘丹栗程. 补体受体C3aR、CD11b在类风湿关节炎的免疫学机制及意义.诊断学,2018-09.

Changes of pulmonary intercellular adhesion molecule-1 and CD11b／CD18 in peripheral polymorphonuclear neutrophils and their significance at the early stage of burns

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Changes of pulmonary intercellular adhesion molecule-1 and CD11b／CD18 in peripheral polymorphonuclear neutrophils and their significance at the early stage of burns

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