Effect of Acupuncture on Calcitonin in Ovariectomized Rats

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摘要 ObjectiveToExplorethemechanismoftheacupunctureonposanenopausalosteoporo-sis.MethodOnehundredWistarfemalerats(6month-old)wererandomlydividedintotwogroups:O-variectomizedgroupandsham-operatedgroup.After3monthsofoperation,threeratswerechosentomeasurethebonehistomorphometricindexes.Thentheovariectomizedratsweredistributedrandomlytoacupuncturegroupandyigaininggroupandnormalsalinegroupandcontrol2group,theratswererespec-tivelytreatedbyacupunctureandyigainingandnormalsaline.Afterthetreatmentforthreecourse,allratswerecollectedbloodfromtheateriafemoralis,thelevelsofcalcitoninweremeasuredbyIRMA.thebonehistomorphometricindexesandC-cellinthyroidfollicleweredetected.ResultsThelevelsofcalcitoninofacupuncturegroupwereincreasingsignificantlycomparingwiththeyigaininggroupandthenormalsalinegroupandthecontrol2group(p<0.05),buttherewerenoevidentdifferenceinthelevelsofcal-citoninbetweentheacupuncturegroupandthesham-operatedgroup.Themeantrabecularbonewidthandthetmbecuharbonevolume%ofacupuncturegroupwereincreasingmorethanthatofthenormalsalinegroupandthecontrol2group(p<0.05);themeanmarrowcavitywidthandthemarrowcavityvol-ume%werederreasingmorethanthatofthenomalsalinegroupandthecontrol2group(P<0.05);thenumberofC-cellinthyroidfollicleoftheacupuncturegroupwereincreasingmorethanthatoftheothergroupsexceptthesham-operatedgroup.ConclusionAcupuncturecaneffectivelytreatthepost-menopausalosteoporosisbystrengtheningtheabilityoftheC-cellinthyroidfolliclewhichcanimprovethelevelsofcalcitonininserum.
机构地区 不详
出版日期 2003年02月12日(中国期刊网平台首次上网日期,不代表论文的发表时间)
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