Transcriptional regulation of IL—3—dependent survival responses

在线阅读 下载PDF 导出详情
摘要 <正>Asoneofthemostcharacterizedcytokines,interleukin3(IL-3)iswellknownforitssurvivaleffectonbothprogenitorsandmaturebloodcells.Althoughwiththeextensivestudies,thesignalingpathwaysandunderlyingmechanismleadingtosurvivalresponsesofIL-3stillarenotcompletelyunderstood.Recently,anapoptoticgeneticpathwayofC.eleganswassuggestedtobeevolutionallyconservedinthatcontrolsthecytokine-dependentanti-apoptoticresponsesinmammalianhematopoieticcelllineages.Amongthispathway,Ces-2isknowntobethefirstdeathspecificationgeneintheC.eleganspathwayandencodesabZIPfamilytranscriptionalfactorthatsharesthesameDNArecognitionsequencewithanoncoprotein,
机构地区 不详
出处 《细胞研究:英文版》 2002年3期
出版日期 2002年03月13日(中国期刊网平台首次上网日期,不代表论文的发表时间)
  • 相关文献