Observation of the Ultrastructure in Syphilitic Chancres

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摘要 Objective:Tostudytheoccurrenceanddevelopmentofprimarysyphilisfromamorphologicalandstructuralaspect.Results:Thepathologicalchangesofsyphiliticchancreoccurmainlyinthedermallayer,manifestedaspartialthinningorlysisofthecapillarybasalmembrane,proliferationofcapillaryendothelialcells,thickeningofsomecollagenfibersandruptureofcollagenfiberssurroundingT.pallidum,structuraldisruptionoftheaxonsofterminalnerves,disarrangementofthesheathofthemyelinatednervefiberswithseparationoflaminaeandtheattachmentofT.pallidumonitsoutermembrane,appearanceofslightlyswollenT.pallidumintheplasmaofthecapillaryendothelialcellsandfibroblasts,andinfiltrationofneutrophils,macrophagesandplasmacellscontainingT.pallidumanditsdebrisfrequentlylinedbyaclearsheath.Conclusion:Thepathogenesisandinjuryofmechanisminprimarysyphiliscanbeexplainedmorphologicallybyitscharacteristicultrastructuralpathologicalchanges.
机构地区 不详
出版日期 2002年01月11日(中国期刊网平台首次上网日期,不代表论文的发表时间)
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