摘要
Precisionmedicineandpersonalizedtherapyarereceivingincreasedattention,andmolecular-subtypeclassificationhasbecomecrucialinplanningtherapeuticschedulesinclinicalpracticeforpatientswithbreastcancer.Humanepidermalgrowthfactorreceptor2(HER2)isassociatedwithhigh-gradebreasttumors,highratesoflymph-nodeinvolvement,highriskofrecurrence,andhighresistancetogeneralchemotherapy.AnalysisofHER2expressionishighlyimportantfordoctorstoidentifypatientswhocanbenefitfromtrastuzumabtherapyandmonitortheresponseandefficacyoftreatment.Inrecentyears,significanteffortshavebeendevotedtoachievingspecificandnoninvasiveHER2-positivebreastcancerimaginginvivo.Inthiswork,wereviewedexistingliteratureonHER2imaginginthepastdecadeandsummarizedthestudiesfromdifferentpointsofview,suchasimagingmodalitiesandHER2-specificprobes.WeaimedtoimprovetheunderstandingonthetranslationalprocessinmolecularimagingforHER2breastcancer.
出版日期
2017年03月13日(中国期刊网平台首次上网日期,不代表论文的发表时间)