PD-L1 expression associated with better response to EGFR tyrosine kinase inhibitors

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摘要 Cancerevadeshostimmunesurveillancebyusingimmunecheckpoints,whichareinhibitorypathwayscrucialformaintainingself-tolerance1.Tumorcellsexpressmultipleinhibitoryligands,andtumor-infiltratinglymphocytes(TIL)expressavarietyofinhibitoryreceptors.InhibitoryreceptorscytotoxicT-lymphocyte-associatedprotein4(CTLA-4)andprogrammeddeath-1
机构地区 不详
出版日期 2015年02月12日(中国期刊网平台首次上网日期,不代表论文的发表时间)
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